HitPredict

Interactor 1: TEN2 (Q9NT68)
Teneurin-2 (Ten-2) (Protein Odd Oz/ten-m homolog 2) (Tenascin-M2) (Ten-m2) (Teneurin transmembrane protein 2) [Cleaved into: Ten-2, soluble form; Ten-2 intracellular domain (Ten-2 ICD)]
Gene: TENM2

Interactor 2: FBX2 (Q9UK22)
F-box only protein 2
Gene: FBXO2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0043197 - dendritic spine
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 2774 Hs			1 296
+	Hs
		1454331 TEN3_HUMAN (1-2774): 0: 3046: 66.32		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		1236161 TEN4_HUMAN (1-2774): 0: 3034: 62.08		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		1236157 TEN4_HUMAN (1-2774): 0: 3034: 62.08		FBX6_HUMAN (40-296): 2.42e-133: 381: 49.81
+	Hs
		1460861 NOTC3_HUMAN (142-1051): 8.12e-73: 274: 13.00		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		666734 TENA_HUMAN (80-701): 7.02e-56: 219: 13.08		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		666731 TENA_HUMAN (80-701): 7.02e-56: 219: 13.08		FBX6_HUMAN (40-296): 2.42e-133: 381: 49.81
+	Hs
		1324228 VWDE_HUMAN (642-912): 1.19e-51: 204: 23.28		FBX6_HUMAN (40-296): 2.42e-133: 381: 49.81
+	Hs
		1353094 SNED1_HUMAN (134-699): 5.73e-38: 159: 11.00		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		1008029 JAG1_HUMAN (722-1082): 2.27e-26: 121: 13.93		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		1047775 NOTC2_HUMAN (56-747): 1.56e-21: 105: 10.24		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		1460866 JAG2_HUMAN (199-672): 3.74e-14: 81.1: 9.94		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		857586 NOTC1_HUMAN (58-670): 8.03e-11: 70.4: 9.25		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00