Protein: ITB8
Integrin beta-8

Gene: ITB8, ITGB8
Organism: Homo sapiens
Interactions: 41
UniProt ID: P26012

Gene Ontology (top 5):
GO:0001570 - vasculogenesis
GO:0001573 - ganglioside metabolic process
GO:0005178 - integrin binding
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

447983

ITAV
Integrin alpha-V

3

20

Small-scale

0.814

High

376717

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

1

High-throughput

0.691

High

143800

NDKM
Nucleoside diphosphate kinase, mitochondrial

3

2

High-throughput

0.667

High

292487

RHBL1
Rhomboid-related protein 1

2

5

High-throughput

0.628

High

683643

LRC32
Transforming growth factor beta activator LRRC32

2

1

High-throughput

0.601

High

230940

TYOBP
TYRO protein tyrosine kinase-binding protein

2

0

High-throughput

0.576

High

683655

L2HDH
L-2-hydroxyglutarate dehydrogenase, mitochondrial

2

1

High-throughput

0.574

High

683659

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

2

4

High-throughput

0.574

High

683650

NEB2
Neurabin-2

1

12

Small-scale

0.561

High

683647

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.553

High

297091

PAK3
Serine/threonine-protein kinase PAK 3

1

8

High-throughput

0.536

High

683636

RAP1B
Ras-related protein Rap-1b

1

19

High-throughput

0.536

High

683645

MICB
MHC class I polypeptide-related sequence B

1

2

High-throughput

0.536

High

683652

ARP3C
Actin-related protein 3C

1

1

High-throughput

0.536

High

683657

TREX1
Three-prime repair exonuclease 1

1

0

High-throughput

0.513

High

683638

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

3

Small-scale

0.501

High

683642

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

6

High-throughput

0.494

High

60489

SYTC2
Threonine--tRNA ligase 2, cytoplasmic

1

1

High-throughput

0.489

High

683653

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

5

High-throughput

0.489

High

217851

TGON2
Trans-Golgi network integral membrane protein 2

1

12

High-throughput

0.479

High

240797

PRKN
E3 ubiquitin-protein ligase parkin

1

5

High-throughput

0.479

High

683634

CTNB1
Catenin beta-1

1

4

Small-scale

0.479

High

683635

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

683637

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

683641

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

683644

RHEB
GTP-binding protein Rheb

1

9

High-throughput

0.479

High

683639

RL23
Large ribosomal subunit protein uL14

1

0

High-throughput

0.458

High

480712

LEG1
Galectin-1

1

17

High-throughput

0.445

High

593573

GDC
Solute carrier family 25 member 16

1

1

High-throughput

0.437

High

407154

CD3D
T-cell surface glycoprotein CD3 delta chain

1

0

High-throughput

0.426

High

683656

DISC1
Disrupted in schizophrenia 1 protein

1

2

High-throughput

0.417

High

170665

CLGN
Calmegin

1

9

High-throughput

0.407

High

683660

FBX2
F-box only protein 2

1

12

High-throughput

0.407

High

129849

GET1
Guided entry of tail-anchored proteins factor 1

3

0

High-throughput

0.347

High

683649

LMF1
Lipase maturation factor 1

3

0

High-throughput

0.347

High

683658

GINM1
Glycoprotein integral membrane protein 1

3

0

High-throughput

0.347

High

683646

PLGT2
Protein O-glucosyltransferase 2

1

0

High-throughput

0.279

Low

683648

EDC3
Enhancer of mRNA-decapping protein 3

1

0

High-throughput

0.279

Low

683651

TIM29
Mitochondrial import inner membrane translocase subunit Tim29

1

0

High-throughput

0.279

Low

683640

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

High-throughput

0.249

Low

683654

CENPH
Centromere protein H

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025