HitPredict

Interactor 1: ISG15 (P05161)
Ubiquitin-like protein ISG15 (Interferon-induced 15 kDa protein) (Interferon-induced 17 kDa protein) (IP17) (Ubiquitin cross-reactive protein) (hUCRP)
Gene: ISG15

Interactor 2: TPM4 (P67936)
Tropomyosin alpha-4 chain (TM30p1) (Tropomyosin-4)
Gene: TPM4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	33024031, 34599178
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 165 Hs			1 248
+	Hs
		464100 UBC_HUMAN (3-157): 1.06e-61: 203: 32.26		TPM2_HUMAN (4-248): 5.06e-42: 146: 69.39
+	Hs
		425270 ISG15_HUMAN (1-165): 4.03e-49: 157: 100.00		TPM1_HUMAN (4-248): 1.44e-48: 163: 68.16
+	Hs
		425255 ISG15_HUMAN (1-165): 4.03e-49: 157: 100.00		TPM3_HUMAN (4-248): 6.5e-47: 159: 69.39
+	Hs
		425262 ISG15_HUMAN (1-165): 4.03e-49: 157: 100.00		TPM2_HUMAN (4-248): 5.06e-42: 146: 69.39
+	Rn
		1224402 UBC_RAT (2-110): 5.82e-33: 124: 28.44		TPM3_RAT (1-248): 6.79e-50: 165: 75.81
+	Rn
		415088 UBC_RAT (2-110): 5.82e-33: 124: 28.44		TPM1_RAT (4-248): 1.11e-48: 163: 68.57
+	Hs
		462834 UBC_HUMAN (3-157): 1.06e-61: 203: 32.26		LAMB1_HUMAN (4-243): 4.91e-14: 73.5: 16.25