HitPredict

Interactor 1: KAPR (P07278)
cAMP-dependent protein kinase regulatory subunit (cAPK regulatory subunit) (Bypass of cyclase mutations protein 1) (Protein kinase A regulatory subunit) (PKA regulatory subunit)
Gene: BCY1

Interactor 2: KAPR (P07278)
cAMP-dependent protein kinase regulatory subunit (cAPK regulatory subunit) (Bypass of cyclase mutations protein 1) (Protein kinase A regulatory subunit) (PKA regulatory subunit)
Gene: BCY1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.920

The method score is based on:

Property Details
Experiments 26687415, 18467557, 33819633, 18719252, 16683188
Identification Methods pull down, protein complementation assay, two hybrid, dihydrofolate reductase reconstruction
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains cNMP_binding~cNMP_binding, RIIa~RIIa
Common GO terms GO:0000785 - chromatin
GO:0001932 - regulation of protein phosphorylation
GO:0004862 - cAMP-dependent protein kinase inhibitor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 9 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 416
Sc

1 416
+ Ce
+ Bt
+ Hs
+ Sp
+ Ce
+ Zm
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Ce
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024