HitPredict

Interactor 1: TBB5 (P07437)
Tubulin beta chain (Tubulin beta-5 chain)
Gene: TUBB

Interactor 2: KSYK (P43405)
Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)
Gene: SYK

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	9880513
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 444 Hs			1 635
+	Gg
		94429 TBB7_CHICK (1-429): 0: 709: 100.00		KSYK_CHICK (3-634): 0: 560: 76.27
+	Hs
		428077 TBB5_HUMAN (1-429): 0: 709: 100.00		ZAP70_HUMAN (6-635): 0: 535: 53.57
+	Hs
		508174 TBB6_HUMAN (1-432): 0: 703: 92.13		FGFR1_HUMAN (179-635): 7.43e-116: 366: 26.24
+	Hs
		428109 TBB5_HUMAN (1-429): 0: 709: 100.00		EPHA4_HUMAN (329-626): 1.47e-105: 343: 34.54
+	Hs
		872631 TBB4B_HUMAN (1-427): 0: 707: 98.36		EPHA4_HUMAN (329-626): 1.47e-105: 343: 34.54
+	Hs
		872702 TBB2B_HUMAN (1-430): 0: 707: 97.44		EPHA4_HUMAN (329-626): 1.47e-105: 343: 34.54
+	Hs
		872701 TBB6_HUMAN (1-432): 0: 703: 92.13		EPHA4_HUMAN (329-626): 1.47e-105: 343: 34.54
+	Hs
		411549 TBB5_HUMAN (1-429): 0: 709: 100.00		LCK_HUMAN (5-201): 3.03e-71: 240: 23.29
+	Hs
		427991 TBB5_HUMAN (1-429): 0: 709: 100.00		SRC_HUMAN (4-371): 2.15e-70: 239: 15.46
+	Hs
		411668 TBB4B_HUMAN (1-427): 0: 707: 98.36		LCK_HUMAN (5-201): 3.03e-71: 240: 23.29
+	Hs
		338386 TBB3_HUMAN (1-444): 0: 712: 92.57		EGFR_HUMAN (375-619): 8.73e-57: 209: 43.15
+	Hs
		337782 TBB5_HUMAN (1-429): 0: 709: 100.00		EGFR_HUMAN (375-619): 8.73e-57: 209: 43.15
+	Hs
		338266 TBB4B_HUMAN (1-427): 0: 707: 98.36		EGFR_HUMAN (375-619): 8.73e-57: 209: 43.15
+	Hs
		338407 TBB2A_HUMAN (1-430): 0: 704: 96.98		EGFR_HUMAN (375-619): 8.73e-57: 209: 43.15
+	Hs
		338925 TBB6_HUMAN (1-432): 0: 703: 92.13		EGFR_HUMAN (375-619): 8.73e-57: 209: 43.15
+	Hs
		383959 TBB6_HUMAN (1-432): 0: 703: 92.13		ERBB2_HUMAN (375-619): 1.47e-52: 197: 42.34
+	Dm
		337680 TBB1_DROME (1-429): 0: 705: 96.50		SRC64_DROME (9-203): 3.92e-53: 192: 23.08
+	Hs
		428098 TBB5_HUMAN (1-429): 0: 709: 100.00		BLK_HUMAN (162-267): 2.8e-29: 123: 32.43
+	Hs
		428198 TBB5_HUMAN (1-429): 0: 709: 100.00		PTK6_HUMAN (14-200): 1.27e-14: 78.4: 20.87
+	Hs
		933801 TBB4B_HUMAN (1-427): 0: 707: 98.36		PTK6_HUMAN (14-200): 1.27e-14: 78.4: 20.87