HitPredict

Interactor 1: PROF1 (P07737)
Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)
Gene: PFN1

Interactor 2: INF2 (Q27J81)
Inverted formin-2 (HBEBP2-binding protein C)
Gene: INF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0031267 - small GTPase binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 1249
+	Hs
		714970 PROF2_HUMAN (1-140): 1.13e-74: 220: 61.43		INF2_HUMAN (1-1249): 0: 873: 100.00
+	Hs
		430352 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		DIAP3_HUMAN (10-1092): 0: 666: 21.22
+	Hs
		243087 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		DIAP2_HUMAN (10-1018): 0: 642: 21.82
+	Hs
		314830 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		FMNL1_HUMAN (40-1009): 1.21e-173: 545: 19.70
+	Hs
		430307 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		FMNL2_HUMAN (10-1000): 6.58e-174: 545: 19.01
+	Hs
		314847 PROF2_HUMAN (1-140): 1.13e-74: 220: 61.43		FMNL1_HUMAN (40-1009): 1.21e-173: 545: 19.70
+	Hs
		430404 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		FHOD1_HUMAN (8-1069): 2.59e-160: 511: 14.30
+	Hs
		715022 PROF2_HUMAN (1-140): 1.13e-74: 220: 61.43		FHOD1_HUMAN (8-1069): 2.59e-160: 511: 14.30
+	Hs
		237549 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		DIAP1_HUMAN (10-532): 2.88e-73: 269: 21.30
+	Hs
		237564 PROF2_HUMAN (1-140): 1.13e-74: 220: 61.43		DIAP1_HUMAN (10-532): 2.88e-73: 269: 21.30
+	Hs
		430356 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		FMN2_HUMAN (495-827): 8.34e-11: 68.9: 25.71