HitPredict

Interactor 1: PROF1 (P07737)
Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)
Gene: PFN1

Interactor 2: ABI1 (Q8IZP0)
Abl interactor 1 (Abelson interactor 1) (Abi-1) (Abl-binding protein 4) (AblBP4) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Nap1-binding protein) (Nap1BP) (Spectrin SH3 domain-binding protein 1) (e3B1)
Gene: ABI1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0045296 - cadherin binding GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 508
+	Hs
		203199 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		SYNJ1_HUMAN (38-463): 1.36e-41: 161: 11.55
+	Hs
		430183 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		LASP1_HUMAN (285-503): 9.91e-33: 127: 19.28
+	Mm
		923936 PROF1_MOUSE (1-140): 5.37e-77: 226: 95.71		PCLO_MOUSE (91-454): 1.32e-28: 122: 15.39
+	Mm
		1337493 PROF2_MOUSE (1-140): 9.83e-75: 220: 61.43		PCLO_MOUSE (91-454): 1.32e-28: 122: 15.39
+	Hs
		166025 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		SYNJ2_HUMAN (39-458): 2.1e-26: 115: 13.88
+	Hs
		430206 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		SH319_HUMAN (446-503): 2.42e-10: 65.1: 36.21
+	Hs
		430194 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		ITSN1_HUMAN (399-504): 1.82e-09: 62.5: 20.35