HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25192599
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 526
+	Hs
		432365 HS90A_HUMAN (1-732): 0: 1087: 100.00		PPIE_HUMAN (280-514): 1.23e-31: 125: 19.46
+	Hs
		437948 HS90B_HUMAN (19-732): 0: 1059: 86.13		FUS_HUMAN (1-526): 1.99e-39: 152: 100.00
+	Hs
		438624 HS90B_HUMAN (19-732): 0: 1059: 86.13		PPIE_HUMAN (280-514): 1.23e-31: 125: 19.46
+	Hs
		431813 HS90A_HUMAN (1-732): 0: 1087: 100.00		PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00
+	Hs
		538130 ENPL_HUMAN (14-701): 0: 898: 46.78		FUS_HUMAN (1-526): 1.99e-39: 152: 100.00
+	Sc
		365510 HSP82_YEAST (16-732): 0: 907: 60.08		PABP_YEAST (263-381): 1.57e-10: 65.5: 18.49
+	Sc
		376612 HSC82_YEAST (16-732): 0: 902: 59.39		PABP_YEAST (263-381): 1.57e-10: 65.5: 18.49