Interactor 1: HS90A (P07901)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Tumor-specific transplantation 86 kDa antigen) (TSTA)
Gene: Hsp90aa1

Interactor 2: CDC37 (Q61081)
Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) [Cleaved into: Hsp90 co-chaperone Cdc37, N-terminally processed]
Gene: CDC37

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 17189825
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CDC37_M~HSP90, CDC37_N~HSP90
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006457 - protein folding
GO:0032991 - protein-containing complex
GO:0050821 - protein stabilization
and 2 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 733
Mm

1 379
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs
+ Sp
+ Sc
+ Sc
+ Hs

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Last updated: 15 Jul 2024