Protein: RL6A
Large ribosomal subunit protein eL6A (60S ribosomal protein L6-A) (L17) (RP18) (YL16)

Gene: RL6A, RPL6A
Organism: Saccharomyces cerevisiae S288C
Interactions: 234
UniProt ID: Q02326

Gene Ontology (top 5):
GO:0000027 - ribosomal large subunit assembly
GO:0002181 - cytoplasmic translation
GO:0003723 - RNA binding
GO:0003735 - structural constituent of ribosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

782417

RPF2
Ribosome biogenesis protein RPF2

2

1

High-throughput

0.776

High

432673

RL7A
Large ribosomal subunit protein uL30A

1

4

High-throughput

0.618

High

433065

RL6B
Large ribosomal subunit protein eL6B

1

2

High-throughput

0.618

High

434073

RL33A
Large ribosomal subunit protein eL33A

1

2

High-throughput

0.618

High

781249

RL14A
Large ribosomal subunit protein eL14A

1

3

High-throughput

0.618

High

1036303

BRX1
Ribosome biogenesis protein BRX1

1

4

High-throughput

0.618

High

1036296

RQC1
Ribosome quality control complex subunit 1

3

1

Small-scale

0.585

High

410292

RL25
Large ribosomal subunit protein uL23

2

1

High-throughput

0.584

High

433276

RL17A
Large ribosomal subunit protein uL22A

2

2

High-throughput

0.584

High

433801

RL26A
Large ribosomal subunit protein uL24A

2

4

High-throughput

0.584

High

504373

RL31A
Large ribosomal subunit protein eL31A

2

1

High-throughput

0.584

High

513748

RL2A
Large ribosomal subunit protein uL2A

2

2

High-throughput

0.584

High

531855

RL4A
Large ribosomal subunit protein uL4A

2

2

High-throughput

0.584

High

689111

RL16A
Large ribosomal subunit protein uL13A

2

4

High-throughput

0.584

High

750132

MRT4
Ribosome assembly factor MRT4

2

4

Small-scale

0.584

High

792562

RL32
Large ribosomal subunit protein eL32

2

1

High-throughput

0.584

High

916858

DXO
Decapping nuclease RAI1

2

1

Small-scale

0.584

High

924177

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

2

3

High-throughput

0.584

High

1036309

TMA46
Translation machinery-associated protein 46

2

1

High-throughput

0.584

High

817282

ARB1
ABC transporter ATP-binding protein ARB1

2

2

Small-scale

0.558

High

819559

SSB2
Ribosome-associated molecular chaperone SSB2

2

5

High-throughput

0.552

High

804647

SSF1
Ribosome biogenesis protein SSF1

1

0

High-throughput

0.546

High

393199

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.541

High

793516

MAK5
ATP-dependent RNA helicase MAK5

1

6

High-throughput

0.536

High

799762

IF5
Eukaryotic translation initiation factor 5

1

1

High-throughput

0.536

High

802894

DBP8
ATP-dependent RNA helicase DBP8

1

3

High-throughput

0.536

High

923108

BRE5
UBP3-associated protein BRE5

1

5

High-throughput

0.536

High

924316

NOP13
Nucleolar protein 13

1

5

High-throughput

0.536

High

1030556

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

3

High-throughput

0.536

High

826762

DSN1
Kinetochore-associated protein DSN1

2

1

High-throughput

0.533

High

918431

EIF2A
Eukaryotic translation initiation factor 2A

2

1

High-throughput

0.533

High

671036

SIS1
Protein SIS1

1

2

High-throughput

0.515

High

805009

IPI1
Pre-rRNA-processing protein IPI1

1

0

High-throughput

0.513

High

701734

URA7
CTP synthase 1

1

1

High-throughput

0.489

High

722183

XPO1
Exportin-1

1

3

High-throughput

0.489

High

808388

SEC31
Protein transport protein SEC31

1

2

High-throughput

0.489

High

805079

RPF1
Ribosome production factor 1

1

0

High-throughput

0.481

High

725931

PSK1
Serine/threonine-protein kinase PSK1

1

0

High-throughput

0.480

High

154215

RL36B
Large ribosomal subunit protein eL36B

1

2

High-throughput

0.479

High

383180

RLA4
Large ribosomal subunit protein P2B

1

3

High-throughput

0.479

High

383354

RL28
Large ribosomal subunit protein uL15

1

2

High-throughput

0.479

High

383850

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.479

High

409775

RL24A
Large ribosomal subunit protein eL24A

1

3

High-throughput

0.479

High

427410

RLA0
Large ribosomal subunit protein uL10

1

4

High-throughput

0.479

High

427601

RLA1
Large ribosomal subunit protein P1A

1

3

High-throughput

0.479

High

427740

RLA2
Large ribosomal subunit protein P2A

1

3

High-throughput

0.479

High

432902

RL9A
Large ribosomal subunit protein uL6A

1

1

High-throughput

0.479

High

434428

RL15A
Large ribosomal subunit protein eL15A

1

3

High-throughput

0.479

High

434637

RL22A
Large ribosomal subunit protein eL22A

1

2

High-throughput

0.479

High

436495

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

4

High-throughput

0.479

High

438759

SC160
Protein SCP160

1

5

High-throughput

0.479

High

442066

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

482077

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

1

High-throughput

0.479

High

503425

RL11A
Large ribosomal subunit protein uL5A

1

4

High-throughput

0.479

High

503837

RL27A
Large ribosomal subunit protein eL27A

1

2

High-throughput

0.479

High

509921

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

1

3

High-throughput

0.479

High

511267

RL20B
Large ribosomal subunit protein eL20B

1

1

High-throughput

0.479

High

689269

RL16B
Large ribosomal subunit protein uL13B

1

4

High-throughput

0.479

High

511475

RL43B
Large ribosomal subunit protein eL43B

1

2

High-throughput

0.479

High

511589

RL44B
Large ribosomal subunit protein eL42B

1

1

High-throughput

0.479

High

512601

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

513402

RL23B
Large ribosomal subunit protein uL14B

1

1

High-throughput

0.479

High

513553

RL1A
Large ribosomal subunit protein uL1A

1

2

High-throughput

0.479

High

514052

RL18B
Large ribosomal subunit protein eL18B

1

1

High-throughput

0.479

High

514346

RL12B
Large ribosomal subunit protein uL11B

1

1

High-throughput

0.479

High

515159

RL19B
Large ribosomal subunit protein eL19

1

3

High-throughput

0.479

High

528859

RLA3
Large ribosomal subunit protein P1B

1

3

High-throughput

0.479

High

569847

RL30
Large ribosomal subunit protein eL30

1

2

High-throughput

0.479

High

570117

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.479

High

601111

RL8A
Large ribosomal subunit protein eL8A

1

4

High-throughput

0.479

High

663713

RL24B
Large ribosomal subunit protein eL24B

1

3

High-throughput

0.479

High

674784

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

676764

GBP2
Serine/arginine

1

3

High-throughput

0.479

High

677531

KRR1
KRR1 small subunit processome component

1

2

High-throughput

0.479

High

678731

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

2

Small-scale

0.479

High

679986

CDC48
Cell division control protein 48

1

3

High-throughput

0.479

High

684820

RL5
Large ribosomal subunit protein uL18

1

3

High-throughput

0.479

High

712651

RL8B
Large ribosomal subunit protein eL8B

1

4

High-throughput

0.479

High

727259

HS104
Heat shock protein 104

1

2

High-throughput

0.479

High

734185

EF2
Elongation factor 2

1

1

Small-scale

0.479

High

744251

ECM32
Putative ATP-dependent RNA helicase ECM32

1

3

High-throughput

0.479

High

747533

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.479

High

753536

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.479

High

781646

DBP7
ATP-dependent RNA helicase DBP7

1

7

High-throughput

0.479

High

792197

GBLP
Small ribosomal subunit protein RACK1

1

4

High-throughput

0.479

High

806161

NMD3
60S ribosomal export protein NMD3

1

1

High-throughput

0.479

High

809395

STM1
Suppressor protein STM1

1

1

High-throughput

0.479

High

812584

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

813960

RBG1
Ribosome-interacting GTPase 1

1

2

High-throughput

0.479

High

814025

IF2P
Eukaryotic translation initiation factor 5B

1

2

High-throughput

0.479

High

820947

RL13B
Large ribosomal subunit protein eL13B

1

2

High-throughput

0.479

High

825897

RL34B
Large ribosomal subunit protein eL34B

1

3

High-throughput

0.479

High

827586

RLP7
Ribosome biogenesis protein RLP7

1

4

High-throughput

0.479

High

835869

RL10
Large ribosomal subunit protein uL16

1

2

High-throughput

0.479

High

850163

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

3

High-throughput

0.479

High

863868

RL17B
Large ribosomal subunit protein uL22B

1

2

High-throughput

0.479

High

879836

RL37A
Large ribosomal subunit protein eL37A

1

2

High-throughput

0.479

High

879883

RL38
Large ribosomal subunit protein eL38

1

1

High-throughput

0.479

High

917677

LSG1
Large subunit GTPase 1

1

2

High-throughput

0.479

High

918323

RL26B
Large ribosomal subunit protein uL24B

1

4

High-throughput

0.479

High

918958

PESC
Pescadillo homolog

1

1

High-throughput

0.479

High

924048

JJJ1
J protein JJJ1

1

9

High-throughput

0.479

High

924241

IPI3
Pre-rRNA-processing protein IPI3

1

2

High-throughput

0.479

High

924706

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

1

Small-scale

0.479

High

924832

NOP15
Ribosome biogenesis protein 15

1

3

High-throughput

0.479

High

932177

RL15B
Large ribosomal subunit protein eL15B

1

3

High-throughput

0.479

High

942016

RL22B
Large ribosomal subunit protein eL22B

1

2

High-throughput

0.479

High

1018148

RL34A
Large ribosomal subunit protein eL34A

1

3

High-throughput

0.479

High

1036280

RL21A
Large ribosomal subunit protein eL21A

1

1

High-throughput

0.479

High

1036282

SYH1
SMY2 homolog 2

1

1

High-throughput

0.479

High

1036284

HAS1
ATP-dependent RNA helicase HAS1

1

7

High-throughput

0.479

High

1036288

HMO1
High mobility group protein 1

1

2

High-throughput

0.479

High

1036290

DHR1
Probable ATP-dependent RNA helicase DHR1

1

3

High-throughput

0.479

High

1036291

VMS1
tRNA endonuclease VMS1

1

1

High-throughput

0.479

High

1036294

LTN1
E3 ubiquitin-protein ligase listerin

1

2

Small-scale

0.479

High

1036298

NOC4
Nucleolar complex protein 4

1

2

High-throughput

0.479

High

1036304

REXO4
RNA exonuclease 4

1

1

High-throughput

0.479

High

1036313

YRA1
RNA annealing protein YRA1

1

4

High-throughput

0.479

High

1036314

DBP10
ATP-dependent RNA helicase DBP10

1

5

High-throughput

0.479

High

149908

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

382985

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.458

High

415044

RL39
Large ribosomal subunit protein eL39

1

0

High-throughput

0.458

High

435298

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

436118

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

455216

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

503194

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

513167

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

514785

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

657121

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

Small-scale

0.458

High

689613

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

734832

SRP21
Signal recognition particle subunit SRP21

1

0

High-throughput

0.458

High

778489

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

796889

GID4
GID complex substrate-recognition subunit 4

1

0

High-throughput

0.458

High

802334

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

806647

RIX1
Pre-rRNA-processing protein RIX1

1

0

Small-scale

0.458

High

806803

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

874477

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

1033512

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

1036281

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.458

High

1036292

GRH1
GRASP65 homolog protein 1

1

0

High-throughput

0.458

High

1036299

ELP1
Elongator complex protein 1

1

0

High-throughput

0.458

High

1036307

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

1036312

CHS5
Chitin biosynthesis protein CHS5

1

0

High-throughput

0.458

High

518112

SSBP1
Single-stranded nucleic acid-binding protein

1

3

High-throughput

0.457

High

864420

IKS1
Probable serine/threonine-protein kinase IKS1

1

1

High-throughput

0.457

High

509688

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

4

High-throughput

0.445

High

545956

SSB1
Ribosome-associated molecular chaperone SSB1

1

5

High-throughput

0.445

High

584264

MS116
ATP-dependent RNA helicase MSS116, mitochondrial

1

6

High-throughput

0.445

High

632721

DBP4
ATP-dependent RNA helicase HCA4

1

8

High-throughput

0.445

High

742212

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.445

High

744010

RAD23
UV excision repair protein RAD23

1

2

High-throughput

0.445

High

776491

MPE1
Protein MPE1

1

1

High-throughput

0.445

High

837285

REF2
RNA end formation protein 2

1

1

High-throughput

0.445

High

1036311

NOP53
Ribosome biogenesis protein NOP53

1

1

Small-scale

0.445

High

448783

SNF1
Carbon catabolite-derepressing protein kinase

1

1

Small-scale

0.437

High

558840

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.437

High

567702

ACOX
Acyl-coenzyme A oxidase

1

1

High-throughput

0.437

High

649659

KCC2
Calcium/calmodulin-dependent protein kinase II

1

2

High-throughput

0.437

High

666530

DBP2
ATP-dependent RNA helicase DBP2

1

1

High-throughput

0.437

High

707946

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

737930

HOG1
Mitogen-activated protein kinase HOG1

1

1

High-throughput

0.437

High

745101

AFG2
ATPase family gene 2 protein

1

3

High-throughput

0.437

High

752633

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.437

High

763847

SKI2
Antiviral helicase SKI2

1

2

High-throughput

0.437

High

780055

EAP1
Protein EAP1

1

1

High-throughput

0.437

High

790281

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

1

High-throughput

0.437

High

793305

RDH54
DNA repair and recombination protein RDH54

1

3

High-throughput

0.437

High

795159

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

798289

ENP1
Essential nuclear protein 1

1

1

High-throughput

0.437

High

798695

YB8A
Putative uncharacterized protein YBR285W

1

1

Small-scale

0.437

High

808954

LCF3
Long-chain-fatty-acid--CoA ligase 3

1

1

High-throughput

0.437

High

812108

DHH1
ATP-dependent RNA helicase DHH1

1

5

High-throughput

0.437

High

813713

ECM1
Shuttling pre-60S factor ECM1

1

1

High-throughput

0.437

High

824933

TM108
Protein TMA108

1

1

High-throughput

0.437

High

826269

SNL1
HSP70 co-chaperone SNL1

1

1

Small-scale

0.437

High

844341

ELP2
Elongator complex protein 2

1

3

High-throughput

0.437

High

844581

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.437

High

864185

ALB1
Ribosome biogenesis protein ALB1

1

1

High-throughput

0.437

High

865710

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.437

High

916945

VID30
GID complex subunit 1

1

1

High-throughput

0.437

High

917890

MRH4
ATP-dependent RNA helicase MRH4, mitochondrial

1

2

High-throughput

0.437

High

918661

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.437

High

921157

H1
Histone H1

1

1

High-throughput

0.437

High

922680

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

1

Small-scale

0.437

High

923187

NOG2
Nucleolar GTP-binding protein 2

1

2

Small-scale

0.437

High

923859

GIS2
Zinc finger protein GIS2

1

3

High-throughput

0.437

High

925371

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.437

High

925425

FAP1
FKBP12-associated protein 1

1

1

High-throughput

0.437

High

932215

ORC1
Origin recognition complex subunit 1

1

2

High-throughput

0.437

High

1018318

CTR9
RNA polymerase-associated protein CTR9

1

2

High-throughput

0.437

High

1036283

TOM1
E3 ubiquitin-protein ligase TOM1

1

3

High-throughput

0.437

High

1036286

ARX1
Probable metalloprotease ARX1

1

3

High-throughput

0.437

High

1036287

RUVB1
RuvB-like protein 1

1

3

High-throughput

0.437

High

1036289

RRP17
Ribosomal RNA-processing protein 17

1

1

High-throughput

0.437

High

1036293

POB3
FACT complex subunit POB3

1

1

High-throughput

0.437

High

1036297

RRP15
Ribosomal RNA-processing protein 15

1

1

Small-scale

0.437

High

1036300

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

1036302

SDO1
Ribosome maturation protein SDO1

1

1

High-throughput

0.437

High

1036305

SGO1
Shugoshin

1

1

High-throughput

0.437

High

1036308

AP3D
AP-3 complex subunit delta

1

1

High-throughput

0.437

High

1036315

RUVB2
RuvB-like protein 2

1

3

High-throughput

0.437

High

1036316

RQC2
Ribosome quality control complex subunit 2

1

1

High-throughput

0.437

High

618918

ARF2
ADP-ribosylation factor 2

1

0

High-throughput

0.426

High

807915

BFR1
Nuclear segregation protein BFR1

1

0

High-throughput

0.426

High

820829

RUXG
Small nuclear ribonucleoprotein G

1

0

High-throughput

0.426

High

739905

RPD3
Histone deacetylase RPD3

1

4

High-throughput

0.407

High

790515

CCL1
Cyclin CCL1

1

2

High-throughput

0.407

High

704697

PRR1
Serine/threonine-protein kinase PRR1

1

0

High-throughput

0.261

Low

402095

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.249

Low

477614

MYO1
Myosin-1

1

0

Small-scale

0.249

Low

561328

DPOLA
DNA polymerase alpha catalytic subunit A

1

0

High-throughput

0.249

Low

678253

BUD23
18S rRNA

1

0

High-throughput

0.249

Low

803659

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.249

Low

805752

YHS7
Uncharacterized protein YHR127W

1

0

High-throughput

0.249

Low

814369

NOC2
Nucleolar complex protein 2

1

0

Small-scale

0.249

Low

821063

LDO16
Lipid droplet organization protein LDO16

1

0

High-throughput

0.249

Low

824637

YIQ1
Uncharacterized protein YIL161W

1

0

High-throughput

0.249

Low

871844

UPF3
Nonsense-mediated mRNA decay protein 3

1

0

High-throughput

0.249

Low

877884

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

916979

EDC1
Enhancer of mRNA-decapping protein 1

1

0

High-throughput

0.249

Low

918609

SLX9
Ribosome biogenesis protein SLX9

1

0

High-throughput

0.249

Low

924364

MDG1
Signal transduction protein MDG1

1

0

High-throughput

0.249

Low

924938

NST1
Stress response protein NST1

1

0

High-throughput

0.249

Low

1036285

ESC1
Silent chromatin protein ESC1

1

0

High-throughput

0.249

Low

1036301

CMS1
Protein CMS1

1

0

High-throughput

0.249

Low

1036306

TMA16
Translation machinery-associated protein 16

1

0

High-throughput

0.249

Low

1036310

KAD6
Adenylate kinase isoenzyme 6 homolog FAP7

1

0

Small-scale

0.249

Low

635983

ODO1
2-oxoglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.232

Low

668498

MED19
Mediator of RNA polymerase II transcription subunit 19

1

0

High-throughput

0.232

Low

700281

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

0

High-throughput

0.232

Low

836853

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

918042

CGR1
rRNA-processing protein CGR1

1

0

High-throughput

0.232

Low

918284

YG1I
Uncharacterized membrane protein YGR026W

1

0

High-throughput

0.232

Low

1036295

ERP1
Protein ERP1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025