HitPredict

Interactor 1: YES (P07947)
Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)
Gene: YES1

Interactor 2: CXA1 (P17302)
Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein)
Gene: GJA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005102 - signaling receptor binding GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 543 Hs			1 382
+	Rn
		435433 SRC_RAT (1-543): 0: 600: 73.67		CXA1_RAT (1-382): 0: 546: 97.64
+	Hs
		522752 SRC_HUMAN (1-543): 0: 601: 74.22		CXA1_HUMAN (1-382): 0: 545: 100.00
+	Mm
		403416 SRC_MOUSE (1-543): 0: 598: 73.67		CXA1_MOUSE (1-382): 0: 544: 97.38
+	Hs
		566936 EPHA3_HUMAN (3-535): 2.01e-156: 473: 25.84		CXA1_HUMAN (1-382): 0: 545: 100.00
+	Hs
		566985 EPHA4_HUMAN (4-542): 2.62e-155: 470: 25.00		CXA1_HUMAN (1-382): 0: 545: 100.00
+	Hs
		433391 YES_HUMAN (1-543): 0: 617: 100.00		CXB7_HUMAN (4-234): 1.64e-104: 309: 41.81
+	Hs
		433414 YES_HUMAN (1-543): 0: 617: 100.00		CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39
+	Hs
		412232 FYN_HUMAN (1-543): 0: 582: 72.16		CXB7_HUMAN (4-234): 1.64e-104: 309: 41.81
+	Hs
		337394 ABL1_HUMAN (41-543): 5.93e-161: 489: 39.10		CXA8_HUMAN (1-382): 1.55e-135: 395: 37.81
+	Hs
		433835 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		CXB7_HUMAN (4-234): 1.64e-104: 309: 41.81
+	Hs
		433886 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39