Interactor 1: TPM2 (P07951)
Tropomyosin beta chain (Beta-tropomyosin) (Tropomyosin-2)
Gene: TPM2

Interactor 2: TPM1 (P09493)
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)
Gene: TPM1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.947

The method score is based on:

Property Details
Experiments 30021884, 3857586, 26186194, 28514442, 33961781, 35235311
Identification Methods proximity labelling technology, pull down, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Tropomyosin~Tropomyosin
Common GO terms GO:0003779 - actin binding
GO:0005829 - cytosol
GO:0005862 - muscle thin filament tropomyosin
GO:0005884 - actin filament
GO:0007015 - actin filament organization
and 5 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 284
Hs

1 284
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024