Interactor 1: ERCC1 (P07992)
DNA excision repair protein ERCC-1
Gene: ERCC1

Interactor 2: XPA (P23025)
DNA repair protein complementing XP-A cells (Xeroderma pigmentosum group A-complementing protein)
Gene: XPA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.766

The method score is based on:

Property Details
Experiments 24036546, 17948053, 32296183, 8197174, 7598728, 26186194, 28514442, 9013642, 18597777, 33961781, 7891694, 19056823, 7876167, 16491090, 8972858, unassigned1304, 25416956, 11058119
Identification Methods fluorescent resonance energy transfer, unspecified method, x-ray crystallography, biochemical, two hybrid, pull down, affinity chromatography technology, surface plasmon resonance, validated two hybrid, anti tag coimmunoprecipitation and 5 others

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Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000110 - nucleotide-excision repair factor 1 complex
GO:0003684 - damaged DNA binding
GO:0005654 - nucleoplasm
GO:0006281 - DNA repair
GO:0006289 - nucleotide-excision repair
and 2 others

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Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 297
Hs

1 273
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024