Interactor 1: TSP1 (P07996)
Thrombospondin-1 (Glycoprotein G)
Gene: THBS1

Interactor 2: LRP2 (P98164)
Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)
Gene: LRP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 7775583
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains EGF_3~EGF_CA, Ldl_recept_a~TSP_1, EGF_CA~TSP_3
Common GO terms GO:0005509 - calcium ion binding
GO:0005783 - endoplasmic reticulum
GO:0009897 - external side of plasma membrane
GO:0043066 - negative regulation of apoptotic process
GO:0070062 - extracellular exosome
and 1 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1170
Hs

1 4655
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024