HitPredict

Interactor 1: PBS2 (P08018)
MAP kinase kinase PBS2 (EC 2.7.12.2) (Polymyxin B resistance protein 2) (Suppressor of fluoride sensitivity 4)
Gene: PBS2

Interactor 2: MYO5 (Q04439)
Myosin-5 (Actin-dependent myosin-I MYO5) (Class I unconventional myosin MYO5) (Type I myosin MYO5)
Gene: MYO5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	19841731
Identification Methods	two hybrid pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0007015 - actin filament organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 668 Sc			1 1219
+	At
		98846 KIN10_ARATH (359-665): 2.1e-128: 390: 22.90		MYO17_ARATH (6-1105): 0: 1111: 27.49
+	Zm
		21875 O49975_MAIZE (316-642): 3.21e-112: 343: 36.50		A0A1D6HXR0_MAIZE (6-1110): 0: 1080: 26.50
+	Hs
		681696 AKT1_HUMAN (311-655): 1.71e-126: 384: 21.75		MYH9_HUMAN (7-1119): 0: 1017: 23.96
+	Hs
		568567 KAPCA_HUMAN (322-666): 6.24e-127: 381: 22.16		MYH9_HUMAN (7-1119): 0: 1017: 23.96
+	Hs
		568568 KAPCA_HUMAN (322-666): 6.24e-127: 381: 22.16		MYH10_HUMAN (2-1099): 0: 1013: 24.07
+	Hs
		528359 KAPCB_HUMAN (322-659): 1.27e-126: 380: 22.90		MYH6_HUMAN (5-830): 0: 1008: 30.73
+	Hs
		610795 KAPCB_HUMAN (322-659): 1.27e-126: 380: 22.90		MYH2_HUMAN (5-830): 0: 1006: 31.42
+	Hs
		522538 KAPCB_HUMAN (322-659): 1.27e-126: 380: 22.90		MYH1_HUMAN (5-830): 0: 1002: 30.57
+	Hs
		610802 KAPCB_HUMAN (322-659): 1.27e-126: 380: 22.90		MYH4_HUMAN (5-818): 0: 1002: 31.11
+	Mm
		554927 KPCE_MOUSE (261-625): 2.28e-105: 338: 24.87		MYH7_MOUSE (2-949): 0: 1030: 27.99
+	Hs
		522609 STK4_HUMAN (346-650): 5.8e-108: 337: 32.80		MYH7_HUMAN (2-949): 0: 1030: 28.20
+	Mm
		554901 KPCE_MOUSE (261-625): 2.28e-105: 338: 24.87		MYH6_MOUSE (3-980): 0: 1016: 27.60
+	Hs
		724784 KPCE_HUMAN (261-665): 6.02e-105: 337: 23.83		MYH9_HUMAN (7-1119): 0: 1017: 23.96
+	Hs
		528408 STK4_HUMAN (346-650): 5.8e-108: 337: 32.80		MYH8_HUMAN (5-830): 0: 1012: 31.37
+	Hs
		528369 STK4_HUMAN (346-650): 5.8e-108: 337: 32.80		MYH6_HUMAN (5-830): 0: 1008: 30.73
+	Hs
		1023137 STK4_HUMAN (346-650): 5.8e-108: 337: 32.80		MYH2_HUMAN (5-830): 0: 1006: 31.42
+	Hs
		522545 STK4_HUMAN (346-650): 5.8e-108: 337: 32.80		MYH1_HUMAN (5-830): 0: 1002: 30.57
+	Hs
		214695 AKT3_HUMAN (308-655): 4e-126: 383: 20.73		MYO1B_HUMAN (36-730): 5.19e-171: 538: 39.72
+	Hs
		117684 STK3_HUMAN (339-646): 2.86e-107: 335: 33.76		MYO1C_HUMAN (31-736): 0: 570: 41.82
+	Hs
		682219 AKT2_HUMAN (315-655): 1.72e-127: 387: 20.57		MYO5A_HUMAN (712-1118): 1.31e-10: 68.2: 9.31