Protein: ASCC3
Activating signal cointegrator 1 complex subunit 3 (EC 5.6.2.4) (ASC-1 complex subunit p200) (ASC1p200) (Helicase, ATP binding 1) (Trip4 complex subunit p200)

Gene: ASCC3
Organism: Homo sapiens
Interactions: 182
UniProt ID: Q8N3C0

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1151353

TRIP4
Activating signal cointegrator 1

5

2

Small-scale

0.912

High

1324995

DNJC7
DnaJ homolog subfamily C member 7

3

12

High-throughput

0.839

High

992854

RACK1
Small ribosomal subunit protein RACK1

2

18

High-throughput

0.776

High

346063

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

13

High-throughput

0.754

High

1227054

A16L1
Autophagy-related protein 16-1

2

19

High-throughput

0.754

High

1324970

ASCC1
Activating signal cointegrator 1 complex subunit 1

6

3

Small-scale

0.739

High

1325006

ASCC2
Activating signal cointegrator 1 complex subunit 2

6

0

Small-scale

0.706

High

857501

NOTC1
Neurogenic locus notch homolog protein 1

1

2

High-throughput

0.691

High

1066393

RBBP4
Histone-binding protein RBBP4

1

12

High-throughput

0.691

High

1313579

DDX60
Probable ATP-dependent RNA helicase DDX60

1

17

High-throughput

0.691

High

1324993

ALKB3
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3

4

0

Small-scale

0.664

High

1111417

DGKZ
Diacylglycerol kinase zeta

1

0

High-throughput

0.656

High

258981

DNJA2
DnaJ homolog subfamily A member 2

3

7

High-throughput

0.650

High

658271

RS3
Small ribosomal subunit protein uS3

3

3

Small-scale

0.650

High

171899

ZN263
Zinc finger protein 263

2

1

High-throughput

0.628

High

131469

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

9

High-throughput

0.618

High

141571

DDX3X
ATP-dependent RNA helicase DDX3X

1

11

High-throughput

0.618

High

315771

RECQ4
ATP-dependent DNA helicase Q4

1

17

High-throughput

0.618

High

684307

DDX6
Probable ATP-dependent RNA helicase DDX6

1

17

High-throughput

0.618

High

731461

STIP1
Stress-induced-phosphoprotein 1

1

10

High-throughput

0.618

High

1088446

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

14

High-throughput

0.618

High

1295485

MIB1
E3 ubiquitin-protein ligase MIB1

1

4

High-throughput

0.618

High

1324973

DCA11
DDB1- and CUL4-associated factor 11

1

16

High-throughput

0.618

High

1324983

FBXW7
F-box/WD repeat-containing protein 7

1

15

High-throughput

0.618

High

1325004

PAIP1
Polyadenylate-binding protein-interacting protein 1

1

3

High-throughput

0.618

High

586781

RS2
Small ribosomal subunit protein uS5

2

1

High-throughput

0.611

High

888468

TSP3
Thrombospondin-3

3

2

High-throughput

0.609

High

508270

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

8

High-throughput

0.602

High

860835

RS10
Small ribosomal subunit protein eS10

2

3

High-throughput

0.601

High

922745

CCHL
Holocytochrome c-type synthase

2

0

High-throughput

0.595

High

188006

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

16

High-throughput

0.575

High

396496

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

401134

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

4

High-throughput

0.571

High

1254618

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.553

High

1325024

HECD1
E3 ubiquitin-protein ligase HECTD1

1

15

High-throughput

0.553

High

74547

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

9

High-throughput

0.536

High

161826

RIOK3
Serine/threonine-protein kinase RIO3

1

8

High-throughput

0.536

High

288699

NPM3
Nucleoplasmin-3

1

6

High-throughput

0.536

High

295210

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

11

High-throughput

0.536

High

443438

CDK1
Cyclin-dependent kinase 1

1

5

High-throughput

0.536

High

447214

NPM
Nucleophosmin

1

6

High-throughput

0.536

High

581563

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

1

1

High-throughput

0.536

High

862899

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

5

High-throughput

0.536

High

872526

SOX2
Transcription factor SOX-2

1

16

High-throughput

0.536

High

884160

SRP09
Signal recognition particle 9 kDa protein

1

2

High-throughput

0.536

High

939384

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

7

High-throughput

0.536

High

969973

RS16
Small ribosomal subunit protein uS9

1

4

High-throughput

0.536

High

973233

RS13
Small ribosomal subunit protein uS15

1

3

High-throughput

0.536

High

973502

RS11
Small ribosomal subunit protein uS17

1

1

High-throughput

0.536

High

979058

RS6
Small ribosomal subunit protein eS6

1

3

High-throughput

0.536

High

1100894

G3BP1
Ras GTPase-activating protein-binding protein 1

1

9

High-throughput

0.536

High

1126472

CAPR1
Caprin-1

1

4

High-throughput

0.536

High

1144070

TEBP
Prostaglandin E synthase 3

1

3

High-throughput

0.536

High

1291062

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

9

High-throughput

0.536

High

1324976

PSPC1
Paraspeckle component 1

1

20

High-throughput

0.536

High

1324985

TRI52
E3 ubiquitin-protein ligase TRIM52

1

11

High-throughput

0.536

High

1324987

EFMT3
EEF1A lysine methyltransferase 3

1

9

High-throughput

0.536

High

1324990

PABP5
Polyadenylate-binding protein 5

1

12

High-throughput

0.536

High

1324996

RBM4B
RNA-binding protein 4B

1

16

High-throughput

0.536

High

1325000

UBXN6
UBX domain-containing protein 6

1

1

High-throughput

0.536

High

1325008

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

1

High-throughput

0.536

High

1325019

SRP68
Signal recognition particle subunit SRP68

1

2

High-throughput

0.536

High

1325021

HSPB8
Heat shock protein beta-8

1

2

High-throughput

0.536

High

1325026

G3BP2
Ras GTPase-activating protein-binding protein 2

1

9

High-throughput

0.536

High

474821

VIME
Vimentin

1

4

High-throughput

0.515

High

192730

ARPC5
Actin-related protein 2/3 complex subunit 5

1

0

High-throughput

0.513

High

261524

B4GT2
Beta-1,4-galactosyltransferase 2

1

0

High-throughput

0.513

High

347168

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.513

High

407111

HG2A
HLA class II histocompatibility antigen gamma chain

1

0

High-throughput

0.513

High

892976

ENTP1
Ectonucleoside triphosphate diphosphohydrolase 1

1

0

High-throughput

0.513

High

1022424

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.513

High

1064583

HDHD1
Pseudouridine-5'-phosphatase

1

0

High-throughput

0.513

High

1242344

PLBL1
Phospholipase B-like 1

1

0

High-throughput

0.513

High

1324972

NT5C
5'(3')-deoxyribonucleotidase, cytosolic type

1

0

High-throughput

0.513

High

1325010

BEX1
Protein BEX1

1

0

High-throughput

0.513

High

1325020

PURG
Purine-rich element-binding protein gamma

1

0

High-throughput

0.513

High

1325025

ABT1
Activator of basal transcription 1

1

0

High-throughput

0.513

High

555508

SKIL
Ski-like protein

1

1

High-throughput

0.508

High

951757

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

6

High-throughput

0.501

High

295606

CIB2
Calcium and integrin-binding family member 2

1

1

High-throughput

0.489

High

1323911

KLH34
Kelch-like protein 34

1

2

High-throughput

0.489

High

1324966

TTC9C
Tetratricopeptide repeat protein 9C

1

2

High-throughput

0.489

High

1324967

OTU6B
Deubiquitinase OTUD6B

1

4

High-throughput

0.489

High

262266

SCN2B
Sodium channel regulatory subunit beta-2

1

0

High-throughput

0.481

High

125528

LEG9
Galectin-9

1

3

High-throughput

0.479

High

132159

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

11

High-throughput

0.479

High

294006

CD123
Translation initiation factor eIF2 assembly protein

1

4

High-throughput

0.479

High

342251

BRD1
Bromodomain-containing protein 1

1

8

High-throughput

0.479

High

372560

MYC
Myc proto-oncogene protein

1

12

High-throughput

0.479

High

412251

NTRK1
High affinity nerve growth factor receptor

1

8

High-throughput

0.479

High

425568

ISG15
Ubiquitin-like protein ISG15

1

12

High-throughput

0.479

High

550360

PABP1
Polyadenylate-binding protein 1

1

14

Small-scale

0.479

High

552636

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

1

High-throughput

0.479

High

558993

LYL1
Protein lyl-1

1

2

High-throughput

0.479

High

573572

ENPL
Endoplasmin

1

9

High-throughput

0.479

High

589147

RFA2
Replication protein A 32 kDa subunit

1

11

High-throughput

0.479

High

642968

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

5

High-throughput

0.479

High

695933

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.479

High

711152

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

2

High-throughput

0.479

High

768635

RFA3
Replication protein A 14 kDa subunit

1

7

High-throughput

0.479

High

831057

CCNF
Cyclin-F

1

6

High-throughput

0.479

High

879267

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

13

High-throughput

0.479

High

883282

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

1

High-throughput

0.479

High

891243

GSK3A
Glycogen synthase kinase-3 alpha

1

13

High-throughput

0.479

High

891674

GSK3B
Glycogen synthase kinase-3 beta

1

15

High-throughput

0.479

High

900412

FXR2
RNA-binding protein FXR2

1

8

High-throughput

0.479

High

954193

RS20
Small ribosomal subunit protein uS10

1

4

High-throughput

0.479

High

970770

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

6

High-throughput

0.479

High

982485

RS15
Small ribosomal subunit protein uS19

1

3

High-throughput

0.479

High

1024696

VIGLN
Vigilin

1

16

High-throughput

0.479

High

1052839

DUSP2
Dual specificity protein phosphatase 2

1

5

High-throughput

0.479

High

1092178

NFX1
Transcriptional repressor NF-X1

1

9

High-throughput

0.479

High

1100118

TIF1B
Transcription intermediary factor 1-beta

1

18

High-throughput

0.479

High

1107920

SQSTM
Sequestosome-1

1

9

High-throughput

0.479

High

1109894

HDAC1
Histone deacetylase 1

1

13

High-throughput

0.479

High

1113676

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1131072

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

7

Small-scale

0.479

High

1155541

EZH2
Histone-lysine N-methyltransferase EZH2

1

8

High-throughput

0.479

High

1161537

IF16
Gamma-interferon-inducible protein 16

1

5

High-throughput

0.479

High

1210908

CE170
Centrosomal protein of 170 kDa

1

6

High-throughput

0.479

High

1276477

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.479

High

1288528

ZN598
E3 ubiquitin-protein ligase ZNF598

1

4

Small-scale

0.479

High

1314308

SLX4
Structure-specific endonuclease subunit SLX4

1

7

High-throughput

0.479

High

1324968

SIR6
NAD-dependent protein deacylase sirtuin-6

1

8

High-throughput

0.479

High

1324969

CGAS
Cyclic GMP-AMP synthase

1

1

High-throughput

0.479

High

1324971

FBX22
F-box only protein 22

1

1

High-throughput

0.479

High

1324974

PDC6I
Programmed cell death 6-interacting protein

1

9

High-throughput

0.479

High

1324975

DCAF4
DDB1- and CUL4-associated factor 4

1

2

High-throughput

0.479

High

1324977

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

1

High-throughput

0.479

High

1324978

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

7

High-throughput

0.479

High

1324979

UBXN4
UBX domain-containing protein 4

1

2

High-throughput

0.479

High

1324981

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1324984

FBX32
F-box only protein 32

1

1

High-throughput

0.479

High

1324986

LRC59
Leucine-rich repeat-containing protein 59

1

3

High-throughput

0.479

High

1324988

PF21A
PHD finger protein 21A

1

20

High-throughput

0.479

High

1324989

DCPS
m7GpppX diphosphatase

1

1

High-throughput

0.479

High

1324992

CI072
Guanine nucleotide exchange factor C9orf72

1

6

High-throughput

0.479

High

1324994

NECD
Necdin

1

8

High-throughput

0.479

High

1324997

TRI56
E3 ubiquitin-protein ligase TRIM56

1

20

High-throughput

0.479

High

1325002

WWTR1
WW domain-containing transcription regulator protein 1

1

19

High-throughput

0.479

High

1325003

MKRN2
E3 ubiquitin-protein ligase makorin-2

1

2

High-throughput

0.479

High

1325005

CCDC8
Coiled-coil domain-containing protein 8

1

4

High-throughput

0.479

High

1325009

TDRD3
Tudor domain-containing protein 3

1

1

High-throughput

0.479

High

1325011

BRD7
Bromodomain-containing protein 7

1

19

High-throughput

0.479

High

1325012

ANLN
Anillin

1

5

High-throughput

0.479

High

1325014

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

8

High-throughput

0.479

High

1325022

RCOR1
REST corepressor 1

1

1

High-throughput

0.479

High

1325023

BRPF3
Bromodomain and PHD finger-containing protein 3

1

8

High-throughput

0.479

High

1325027

CC14A
Dual specificity protein phosphatase CDC14A

1

9

High-throughput

0.479

High

1325028

RBM8A
RNA-binding protein 8A

1

20

High-throughput

0.479

High

733960

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

1

1

High-throughput

0.470

High

246755

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.458

High

593162

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.458

High

1324982

GOGA1
Golgin subfamily A member 1

1

0

High-throughput

0.458

High

1325013

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

High-throughput

0.458

High

1325017

C2D2A
Coiled-coil and C2 domain-containing protein 2A

1

0

High-throughput

0.458

High

1324999

RNF26
E3 ubiquitin-protein ligase RNF26

1

8

Small-scale

0.457

High

1325015

DISC1
Disrupted in schizophrenia 1 protein

1

4

High-throughput

0.457

High

62560

S35F4
Solute carrier family 35 member F4

1

1

High-throughput

0.445

High

939212

SUMO3
Small ubiquitin-related modifier 3

1

7

Small-scale

0.445

High

942743

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

4

High-throughput

0.445

High

1094930

TRAF3
TNF receptor-associated factor 3

1

14

High-throughput

0.445

High

1209383

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

9

High-throughput

0.445

High

1324965

SVOPL
Putative transporter SVOPL

1

2

High-throughput

0.445

High

1249014

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

1250169

LRC31
Leucine-rich repeat-containing protein 31

1

6

High-throughput

0.437

High

1256515

CE128
Centrosomal protein of 128 kDa

1

9

High-throughput

0.437

High

1324991

XAGE2
X antigen family member 2

1

3

High-throughput

0.437

High

1324998

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

4

High-throughput

0.437

High

1325007

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.437

High

1325018

HECW2
E3 ubiquitin-protein ligase HECW2

1

13

High-throughput

0.437

High

1324980

APBP2
Amyloid protein-binding protein 2

1

3

Small-scale

0.408

High

240152

FGF17
Fibroblast growth factor 17

1

4

High-throughput

0.407

High

1325016

PP4RL
Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like

1

2

High-throughput

0.407

High

632934

PRVA
Parvalbumin alpha

1

0

High-throughput

0.279

Low

1099632

NOGG
Noggin

1

0

High-throughput

0.279

Low

1177025

INF2
Inverted formin-2

1

0

High-throughput

0.279

Low

1308359

CCD71
Coiled-coil domain-containing protein 71

1

0

High-throughput

0.249

Low

288186

CLC3A
C-type lectin domain family 3 member A

1

0

High-throughput

0.232

Low

877694

SL9A3
Sodium/hydrogen exchanger 3

1

0

High-throughput

0.232

Low

1070447

ZNFS1
Putative uncharacterized protein ZNF252P-AS1

1

0

High-throughput

0.232

Low

1325001

S6A16
Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025