HitPredict

Interactor 1: CXB1 (P08034)
Gap junction beta-1 protein (Connexin-32) (Cx32) (GAP junction 28 kDa liver protein)
Gene: GJB1

Interactor 2: RON (Q04912)
Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]
Gene: MST1R

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	30401746
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007399 - nervous system development
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 283 Hs			1 1400
+	Hs
		441424 CXA1_HUMAN (2-227): 2.73e-108: 320: 42.45		MET_HUMAN (1-1391): 0: 1065: 32.44
+	Hs
		434822 CXB1_HUMAN (1-283): 6.23e-161: 450: 100.00		EPHB1_HUMAN (557-1377): 9.28e-165: 522: 17.63
+	Hs
		434812 CXB1_HUMAN (1-283): 6.23e-161: 450: 100.00		EPHA1_HUMAN (727-1375): 8.38e-134: 438: 23.79
+	Hs
		566985 CXA1_HUMAN (2-227): 2.73e-108: 320: 42.45		EPHA4_HUMAN (557-1381): 4.36e-174: 547: 17.21
+	Hs
		566936 CXA1_HUMAN (2-227): 2.73e-108: 320: 42.45		EPHA3_HUMAN (568-1377): 1.49e-169: 535: 16.39
+	Hs
		566935 CXA1_HUMAN (2-227): 2.73e-108: 320: 42.45		EPHA2_HUMAN (557-1377): 5.9e-160: 509: 16.75
+	Hs
		566984 CXA1_HUMAN (2-227): 2.73e-108: 320: 42.45		EPHB3_HUMAN (654-1377): 3.03e-157: 502: 17.93
+	Hs
		1072544 CXD3_HUMAN (2-223): 1.1e-90: 272: 38.74		EPHA7_HUMAN (557-1372): 5.26e-172: 542: 17.56
+	Hs
		665269 CXB7_HUMAN (1-216): 7.19e-100: 293: 48.15		EPHA2_HUMAN (557-1377): 5.9e-160: 509: 16.75
+	Hs
		665282 CXD3_HUMAN (2-223): 1.1e-90: 272: 38.74		EPHA2_HUMAN (557-1377): 5.9e-160: 509: 16.75
+	Hs
		872409 CXD3_HUMAN (2-223): 1.1e-90: 272: 38.74		EPHB3_HUMAN (654-1377): 3.03e-157: 502: 17.93
+	Hs
		507909 CXA8_HUMAN (2-277): 2.91e-117: 345: 40.14		FGFR1_HUMAN (767-1397): 8.56e-114: 379: 22.74
+	Hs
		435527 CXA1_HUMAN (2-227): 2.73e-108: 320: 42.45		IGF1R_HUMAN (1072-1343): 3.56e-52: 204: 37.93
+	Hs
		411289 CXA1_HUMAN (2-227): 2.73e-108: 320: 42.45		INSR_HUMAN (1073-1338): 8.47e-51: 199: 38.73
+	Rn
		435256 CXA1_RAT (2-227): 2.82e-108: 320: 42.86		CSK_RAT (1086-1344): 9.45e-51: 188: 40.39
+	Hs
		566953 CXA1_HUMAN (2-227): 2.73e-108: 320: 42.45		CSK_HUMAN (1086-1344): 9.72e-51: 188: 40.00
+	Hs
		433835 CXB7_HUMAN (1-216): 7.19e-100: 293: 48.15		LYN_HUMAN (1088-1357): 6.87e-51: 190: 39.11
+	Hs
		411435 CXD3_HUMAN (2-223): 1.1e-90: 272: 38.74		INSR_HUMAN (1073-1338): 8.47e-51: 199: 38.73
+	Hs
		433886 CXD3_HUMAN (2-223): 1.1e-90: 272: 38.74		LYN_HUMAN (1088-1357): 6.87e-51: 190: 39.11