HitPredict

Interactor 1: TNR16 (P08138)
Tumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (Low-affinity nerve growth factor receptor p75NGFR) (Low-affinity nerve growth factor receptor p75NGR) (p75 ICD) (CD antigen CD271)
Gene: NGFR

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.692

Property	Details
Experiments	10514511, 14960584, 23017601, 11244088
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0042475 - odontogenesis of dentin-containing tooth
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 427 Hs			1 522
+	Rn
		78177 TNR16_RAT (3-427): 3.25e-110: 332: 92.24		TRAF6_RAT (1-522): 7.85e-142: 421: 86.42
+	Hs
		584509 TNR1A_HUMAN (29-417): 1.27e-76: 247: 18.27		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		436618 TNR16_HUMAN (1-427): 1.17e-115: 346: 100.00		TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85
+	Rn
		78206 TNR16_RAT (3-427): 3.25e-110: 332: 92.24		B5DFH7_RAT (40-500): 4.24e-100: 312: 25.81
+	Hs
		436641 TNR16_HUMAN (1-427): 1.17e-115: 346: 100.00		TRAF4_HUMAN (54-500): 6.36e-91: 287: 26.11
+	Hs
		129526 TNR16_HUMAN (1-427): 1.17e-115: 346: 100.00		TRAF5_HUMAN (43-500): 4.95e-87: 280: 25.23
+	Hs
		436620 TNR16_HUMAN (1-427): 1.17e-115: 346: 100.00		TRAF3_HUMAN (19-501): 9.91e-86: 277: 22.18
+	Hs
		591438 TNR1B_HUMAN (8-274): 1.53e-45: 165: 18.32		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Mm
		626852 TNR1A_MOUSE (29-425): 1.22e-78: 252: 17.33		TRAF2_MOUSE (40-500): 3.02e-101: 315: 26.05
+	Hs
		436619 TNR16_HUMAN (1-427): 1.17e-115: 346: 100.00		TRAF1_HUMAN (50-501): 5.58e-64: 216: 19.40
+	Hs
		584390 TNR1A_HUMAN (29-417): 1.27e-76: 247: 18.27		TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85
+	Hs
		584394 TNR1A_HUMAN (29-417): 1.27e-76: 247: 18.27		TRAF3_HUMAN (19-501): 9.91e-86: 277: 22.18
+	Hs
		154352 TR10B_HUMAN (17-424): 1.06e-61: 207: 16.08		TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85
+	Hs
		1020849 TNR25_HUMAN (29-422): 1.33e-58: 198: 18.75		TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85
+	Hs
		301556 TNR16_HUMAN (1-427): 1.17e-115: 346: 100.00		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89
+	Hs
		591317 TNR1B_HUMAN (8-274): 1.53e-45: 165: 18.32		TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85
+	Hs
		584392 TNR1A_HUMAN (29-417): 1.27e-76: 247: 18.27		TRAF1_HUMAN (50-501): 5.58e-64: 216: 19.40
+	Hs
		591320 TNR1B_HUMAN (8-274): 1.53e-45: 165: 18.32		TRAF3_HUMAN (19-501): 9.91e-86: 277: 22.18
+	Hs
		591319 TNR1B_HUMAN (8-274): 1.53e-45: 165: 18.32		TRAF1_HUMAN (50-501): 5.58e-64: 216: 19.40
+	Hs
		301610 TNR1B_HUMAN (8-274): 1.53e-45: 165: 18.32		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89