Protein: KPC1
Protein kinase C-like 1 (PKC 1) (EC 2.7.11.13)

Gene: KPC1, PKC1
Organism: Saccharomyces cerevisiae S288C
Interactions: 120
UniProt ID: P24583

Gene Ontology (top 5):
GO:0000425 - pexophagy
GO:0004674 - protein serine/threonine kinase activity
GO:0004697 - diacylglycerol-dependent serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

448511

RHO1
GTP-binding protein RHO1

11

20

Small-scale

0.979

High

665795

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

2

1

High-throughput

0.817

High

665778

KPC1
Protein kinase C-like 1

2

18

Small-scale

0.767

High

364349

CDK1
Cyclin-dependent kinase 1

1

6

High-throughput

0.724

High

665803

EDE1
EH domain-containing and endocytosis protein 1

1

7

High-throughput

0.691

High

665812

AKL1
Serine/threonine-protein kinase AKL1

1

8

High-throughput

0.691

High

665832

LSB3
LAS seventeen-binding protein 3

1

11

High-throughput

0.691

High

403365

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

6

Small-scale

0.656

High

665790

MKK1
MAP kinase kinase MKK1/SSP32

1

17

Small-scale

0.656

High

665857

PIN3
[PSI+] inducibility protein 3

1

10

High-throughput

0.656

High

665792

PAH1
Phosphatidic acid phosphohydrolase 1

3

1

Small-scale

0.655

High

665842

ZDS2
Protein ZDS2

3

2

Small-scale

0.649

High

656700

KC12
Casein kinase I homolog 2

1

7

High-throughput

0.647

High

665831

FKH2
Fork head protein homolog 2

1

7

Small-scale

0.647

High

665847

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

17

Small-scale

0.647

High

665863

PKH2
Serine/threonine-protein kinase PKH2

1

18

Small-scale

0.647

High

665797

STE5
Protein STE5

1

0

Small-scale

0.645

High

665786

URA7
CTP synthase 1

3

0

Small-scale

0.627

High

548260

FUS1
Nuclear fusion protein FUS1

1

0

High-throughput

0.622

High

665827

SHO1
High osmolarity signaling protein SHO1

1

0

High-throughput

0.622

High

646003

KIN3
Serine/threonine-protein kinase KIN3

1

17

High-throughput

0.621

High

665794

TOR2
Serine/threonine-protein kinase TOR2

2

13

Small-scale

0.602

High

367699

ENO1
Enolase 1

2

3

High-throughput

0.601

High

665845

2ABA
Protein phosphatase PP2A regulatory subunit B

2

7

Small-scale

0.595

High

665782

SYP1
Suppressor of yeast profilin deletion

2

0

Small-scale

0.592

High

665834

BBC1
Myosin tail region-interacting protein MTI1

1

3

High-throughput

0.587

High

392273

HSP82
ATP-dependent molecular chaperone HSP82

1

20

High-throughput

0.575

High

665779

SIS1
Protein SIS1

1

11

High-throughput

0.575

High

665781

MAS5
Mitochondrial protein import protein MAS5

1

7

High-throughput

0.575

High

665799

HSP78
Heat shock protein 78, mitochondrial

2

3

High-throughput

0.571

High

448925

TOP2
DNA topoisomerase 2

1

7

Small-scale

0.568

High

665828

SSB2
Ribosome-associated molecular chaperone SSB2

2

12

High-throughput

0.552

High

665815

NEM1
Nuclear envelope morphology protein 1

2

3

Small-scale

0.550

High

665811

AP2A
AP-2 complex subunit alpha

1

3

High-throughput

0.536

High

665846

RAD25
General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2

1

6

High-throughput

0.515

High

665801

OSTB
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1

1

1

Small-scale

0.504

High

665784

RS5
Small ribosomal subunit protein uS7

1

2

Small-scale

0.501

High

665843

H3
Histone H3

1

9

Small-scale

0.501

High

627747

TYR1
Prephenate dehydrogenase [NADP(+)]

1

0

High-throughput

0.493

High

665817

TRM5
tRNA

1

0

High-throughput

0.493

High

665840

CSL4
Exosome complex component CSL4

1

0

High-throughput

0.493

High

665866

FOLD
Dihydrofolate synthetase

1

0

High-throughput

0.493

High

665791

SMI1
Cell wall assembly regulator SMI1

1

0

Small-scale

0.486

High

665838

TOS2
Protein TOS2

1

0

High-throughput

0.486

High

477517

MYO1
Myosin-1

1

10

High-throughput

0.481

High

647699

RFA1
Replication factor A protein 1

1

6

Small-scale

0.481

High

665785

PRP45
Pre-mRNA-processing protein 45

1

2

Small-scale

0.481

High

665798

SLA2
Protein SLA2

1

6

High-throughput

0.481

High

665802

NUF2
Kinetochore protein NUF2

1

4

High-throughput

0.481

High

665807

DYHC
Dynein heavy chain, cytoplasmic

1

1

High-throughput

0.481

High

665818

LAM4
Membrane-anchored lipid-binding protein LAM4

1

4

High-throughput

0.481

High

665821

END3
Actin cytoskeleton-regulatory complex protein END3

1

2

High-throughput

0.481

High

665823

RGA1
Rho-type GTPase-activating protein 1

1

5

High-throughput

0.481

High

665825

LIS1
Nuclear distribution protein PAC1

1

16

High-throughput

0.481

High

665849

MDM1
Structural protein MDM1

1

2

High-throughput

0.481

High

665865

PRP46
Pre-mRNA-splicing factor PRP46

1

12

Small-scale

0.481

High

633211

KICH
Choline kinase

1

0

Small-scale

0.480

High

636910

FAR1
Cyclin-dependent kinase inhibitor FAR1

1

0

Small-scale

0.480

High

665860

RT109
Histone acetyltransferase RTT109

1

0

Small-scale

0.480

High

665862

NDD1
Nuclear division defective protein 1

1

0

Small-scale

0.480

High

665869

IGO2
mRNA stability protein IGO2

1

0

Small-scale

0.480

High

149602

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

434849

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.479

High

435788

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

665783

CDC48
Cell division control protein 48

1

4

High-throughput

0.479

High

665787

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

665810

GBLP
Small ribosomal subunit protein RACK1

1

17

High-throughput

0.479

High

665814

KPR2
Ribose-phosphate pyrophosphokinase 2

1

14

High-throughput

0.479

High

665848

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

14

Small-scale

0.479

High

665850

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

665852

ESC1
Silent chromatin protein ESC1

1

3

High-throughput

0.470

High

560230

TOP3
DNA topoisomerase 3

1

0

Small-scale

0.460

High

665788

SWC3
SWR1-complex protein 3

1

0

High-throughput

0.460

High

665808

JNM1
Nuclear migration protein JNM1

1

0

High-throughput

0.460

High

665819

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.460

High

665829

CBF3B
Centromere DNA-binding protein complex CBF3 subunit B

1

0

High-throughput

0.460

High

665835

NNF1
Kinetochore-associated protein NNF1

1

0

High-throughput

0.460

High

665839

KNL1
Outer kinetochore KNL1 complex subunit SPC105

1

0

High-throughput

0.460

High

665844

HSK3
DASH complex subunit HSK3

1

0

High-throughput

0.460

High

665854

VPS20
Vacuolar protein sorting-associated protein 20

1

0

High-throughput

0.460

High

665855

FMP27
Protein FMP27, mitochondrial

1

0

High-throughput

0.460

High

665856

EAF1
Chromatin modification-related protein EAF1

1

0

High-throughput

0.460

High

665858

NDE1
Nuclear distribution protein nudE homolog 1

1

0

High-throughput

0.460

High

665796

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

665806

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

665837

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

665853

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

665859

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

523127

HSP71
Heat shock protein SSA1

1

12

High-throughput

0.445

High

525977

HSP72
Heat shock protein SSA2

1

12

High-throughput

0.445

High

543889

SSB1
Ribosome-associated molecular chaperone SSB1

1

12

High-throughput

0.445

High

665789

HS104
Heat shock protein 104

1

3

High-throughput

0.445

High

665793

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

665816

SSZ1
Ribosome-associated complex subunit SSZ1

1

9

High-throughput

0.445

High

665822

TCPG
T-complex protein 1 subunit gamma

1

17

High-throughput

0.445

High

665826

HSP7E
Heat shock protein SSC3, mitochondrial

1

17

High-throughput

0.445

High

665804

CASP
Protein CASP

1

10

High-throughput

0.439

High

665809

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

2

High-throughput

0.439

High

665867

VPS5
Vacuolar protein sorting-associated protein 5

1

5

High-throughput

0.439

High

665868

AP2M
AP-2 complex subunit mu

1

4

Small-scale

0.439

High

383531

RS17A
Small ribosomal subunit protein eS17A

1

2

High-throughput

0.437

High

433463

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.437

High

441720

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

512273

RS6A
Small ribosomal subunit protein eS6A

1

6

High-throughput

0.437

High

512836

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

665780

BPH1
Beige protein homolog 1

1

3

High-throughput

0.437

High

665800

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.437

High

665830

OST1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

Small-scale

0.437

High

665861

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

665833

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

665836

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.426

High

665841

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.426

High

613794

SPO7
Sporulation-specific protein SPO7

2

0

Small-scale

0.314

High

665820

STT3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3

1

0

Small-scale

0.288

High

665851

OSTD
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1

1

0

Small-scale

0.288

High

665864

ATG34
Autophagy-related protein 34

1

0

High-throughput

0.279

Low

665805

BLI1
Biogenesis of lysosome-related organelles complex 1 subunit BLI1

1

0

High-throughput

0.251

Low

665824

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.251

Low

665813

GIP1
GLC7-interacting protein 1

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025