HitPredict

Interactor 1: PFKAM (P08237)
ATP-dependent 6-phosphofructokinase, muscle type (ATP-PFK) (PFK-M) (EC 2.7.1.11) (6-phosphofructokinase type A) (Phosphofructo-1-kinase isozyme A) (PFK-A) (Phosphohexokinase)
Gene: PFKM

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26402096, 35063084
Identification Methods	anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 780 Hs			1 758
+	Hs
		496875 PFKAP_HUMAN (5-771): 0: 1028: 71.75		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Rn
		581946 PFKAM_RAT (1-780): 0: 1063: 96.67		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94170 PFKAM_RAT (1-780): 0: 1063: 96.67		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Mm
		497944 PFKAM_MOUSE (1-780): 0: 1071: 97.82		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Mm
		498160 PFKAP_MOUSE (7-771): 0: 1019: 71.41		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Hs
		496252 PFKAL_HUMAN (6-355): 8.8e-78: 268: 29.51		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Mm
		497913 PFKAL_MOUSE (1-355): 2.6e-79: 272: 29.73		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Rn
		581947 PFKAP_RAT (5-355): 2.32e-68: 242: 28.22		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94171 PFKAP_RAT (5-355): 2.32e-68: 242: 28.22		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56