Protein: TM214
Transmembrane protein 214

Gene: TM214, TMEM214
Organism: Homo sapiens
Interactions: 171
UniProt ID: Q6NUQ4

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0005881 - cytoplasmic microtubule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

163316

TR10B
Tumor necrosis factor receptor superfamily member 10B

3

3

High-throughput

0.667

High

1164045

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

3

1

High-throughput

0.667

High

719953

HMOX2
Heme oxygenase 2

3

0

High-throughput

0.638

High

455978

ASGR2
Asialoglycoprotein receptor 2

4

1

High-throughput

0.630

High

60727

F234B
Protein FAM234B

2

1

High-throughput

0.628

High

252355

TLR2
Toll-like receptor 2

2

2

High-throughput

0.628

High

476501

STS
Steryl-sulfatase

2

2

High-throughput

0.628

High

1238668

ARSG
Arylsulfatase G

2

2

High-throughput

0.628

High

1148227

TLR1
Toll-like receptor 1

2

3

High-throughput

0.611

High

1238658

CGAT1
Chondroitin sulfate N-acetylgalactosaminyltransferase 1

3

1

High-throughput

0.609

High

1238652

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

3

1

High-throughput

0.604

High

762338

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

2

0

High-throughput

0.602

High

1198713

MPPE1
Metallophosphoesterase 1

2

0

High-throughput

0.602

High

1238678

ADPGK
ADP-dependent glucokinase

2

0

High-throughput

0.602

High

595063

KCNA2
Potassium voltage-gated channel subfamily A member 2

2

1

High-throughput

0.601

High

380445

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

3

2

High-throughput

0.599

High

385857

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

2

High-throughput

0.584

High

1238655

NUP43
Nucleoporin Nup43

2

2

High-throughput

0.584

High

396325

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

951210

SC61B
Protein transport protein Sec61 subunit beta

2

0

High-throughput

0.559

High

1238656

NUP35
Nucleoporin NUP35

2

0

High-throughput

0.559

High

1238666

LRC59
Leucine-rich repeat-containing protein 59

2

0

High-throughput

0.559

High

380303

DRA
HLA class II histocompatibility antigen, DR alpha chain

2

2

High-throughput

0.549

High

127691

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

3

High-throughput

0.536

High

890340

NU153
Nuclear pore complex protein Nup153

1

1

High-throughput

0.536

High

907241

ARSL
Arylsulfatase L

1

2

High-throughput

0.536

High

1134237

IMB1
Importin subunit beta-1

1

1

High-throughput

0.536

High

1238667

SEH1
Nucleoporin SEH1

1

1

High-throughput

0.536

High

132607

UPK1A
Uroplakin-1a

1

0

High-throughput

0.513

High

317071

DPM2
Dolichol phosphate-mannose biosynthesis regulatory protein

1

0

High-throughput

0.513

High

376615

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

0

High-throughput

0.513

High

945251

NU107
Nuclear pore complex protein Nup107

1

0

High-throughput

0.513

High

958566

TM258
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258

1

0

High-throughput

0.513

High

1238663

NCLN
BOS complex subunit NCLN

1

0

High-throughput

0.513

High

1238664

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

1238672

RBM18
Probable RNA-binding protein 18

1

0

High-throughput

0.513

High

1238686

DNJC5
DnaJ homolog subfamily C member 5

1

0

High-throughput

0.513

High

283109

PSIP1
PC4 and SFRS1-interacting protein

1

0

High-throughput

0.493

High

164927

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

3

High-throughput

0.489

High

1238680

TLR10
Toll-like receptor 10

1

3

High-throughput

0.489

High

1238682

F234A
Protein FAM234A

1

1

High-throughput

0.489

High

1238707

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.489

High

178030

LSM1
U6 snRNA-associated Sm-like protein LSm1

1

0

High-throughput

0.486

High

126656

RHOD
Rho-related GTP-binding protein RhoD

1

5

High-throughput

0.479

High

178297

NPC1
NPC intracellular cholesterol transporter 1

1

1

High-throughput

0.479

High

373998

RASN
GTPase NRas

1

1

High-throughput

0.479

High

375622

RASK
GTPase KRas

1

1

High-throughput

0.479

High

404134

GCR
Glucocorticoid receptor

1

1

Small-scale

0.479

High

418206

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.479

High

466313

RHOC
Rho-related GTP-binding protein RhoC

1

3

High-throughput

0.479

High

581117

RAC2
Ras-related C3 botulinum toxin substrate 2

1

3

High-throughput

0.479

High

820672

CEAM6
Cell adhesion molecule CEACAM6

1

2

High-throughput

0.479

High

955297

CDC42
Cell division control protein 42 homolog

1

3

High-throughput

0.479

High

962165

RHOA
Transforming protein RhoA

1

4

High-throughput

0.479

High

1058469

CKAP4
Cytoskeleton-associated protein 4

1

1

High-throughput

0.479

High

1238639

TECT3
Tectonic-3

1

1

High-throughput

0.479

High

1238654

DHB11
Estradiol 17-beta-dehydrogenase 11

1

1

High-throughput

0.479

High

1238690

RHOF
Rho-related GTP-binding protein RhoF

1

5

High-throughput

0.479

High

1238704

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

157503

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

173959

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.458

High

212429

SPIT2
Kunitz-type protease inhibitor 2

1

0

High-throughput

0.458

High

218330

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

291387

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.458

High

417504

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

611175

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.458

High

847565

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.458

High

894821

EMD
Emerin

1

0

High-throughput

0.458

High

901314

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.458

High

903959

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

1087151

STX4
Syntaxin-4

1

0

High-throughput

0.458

High

1111572

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.458

High

1125486

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

0

High-throughput

0.458

High

1238640

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1238674

DNJC1
DnaJ homolog subfamily C member 1

1

0

High-throughput

0.458

High

1238676

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.458

High

1238677

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

1238679

DERL1
Derlin-1

1

0

High-throughput

0.458

High

1238681

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.458

High

1238683

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.458

High

1238689

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

1238694

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.458

High

1238696

FBX6
F-box only protein 6

1

0

High-throughput

0.458

High

1238701

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.458

High

1238702

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1238703

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

1238705

SEC63
Translocation protein SEC63 homolog

1

0

High-throughput

0.458

High

1238710

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.458

High

142355

PEX7
Peroxisomal targeting signal 2 receptor

1

1

High-throughput

0.445

High

437708

HEPS
Serine protease hepsin

1

2

High-throughput

0.445

High

1238661

CTL1
Choline transporter-like protein 1

1

1

High-throughput

0.445

High

1238700

SCN3B
Sodium channel regulatory subunit beta-3

1

1

High-throughput

0.445

High

634490

LMNB1
Lamin-B1

1

2

High-throughput

0.437

High

642933

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

1

High-throughput

0.437

High

674209

BRD2
Bromodomain-containing protein 2

1

1

High-throughput

0.437

High

689832

CD27
CD27 antigen

1

3

High-throughput

0.437

High

1004711

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

1201941

BRDT
Bromodomain testis-specific protein

1

1

High-throughput

0.437

High

1238645

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.437

High

1238671

TECT2
Tectonic-2

1

1

High-throughput

0.437

High

1238685

TMPS5
Transmembrane protease serine 5

1

2

High-throughput

0.437

High

161140

ABCD4
Lysosomal cobalamin transporter ABCD4

1

0

High-throughput

0.426

High

253848

TPST2
Protein-tyrosine sulfotransferase 2

1

0

High-throughput

0.426

High

430038

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

1007442

S35B1
Solute carrier family 35 member B1

1

0

High-throughput

0.426

High

1146559

TMED2
Transmembrane emp24 domain-containing protein 2

1

0

High-throughput

0.426

High

1238651

CARME
Carnosine N-methyltransferase

1

0

High-throughput

0.426

High

1238662

EDA
Ectodysplasin-A

1

0

High-throughput

0.426

High

1238698

DDX28
Probable ATP-dependent RNA helicase DDX28

1

0

High-throughput

0.426

High

1238709

S35A3
UDP-N-acetylglucosamine transporter

1

0

High-throughput

0.426

High

94392

D6RAP2
Toll like receptor 1

1

4

High-throughput

0.407

High

97107

E9PMV2
Major histocompatibility complex, class II, DQ alpha 1

1

2

High-throughput

0.407

High

1158729

PSG3
Pregnancy-specific beta-1-glycoprotein 3

1

1

High-throughput

0.407

High

1238648

CTL2
Choline transporter-like protein 2

1

1

High-throughput

0.407

High

1238706

NPCL1
NPC1-like intracellular cholesterol transporter 1

1

1

High-throughput

0.407

High

332655

LYPD3
Ly6/PLAUR domain-containing protein 3

4

0

High-throughput

0.360

High

1010054

DLK1
Protein delta homolog 1

4

0

High-throughput

0.360

High

1192245

ZACN
Ligand-gated cation channel ZACN

3

0

High-throughput

0.347

High

1238646

LYPD6
Ly6/PLAUR domain-containing protein 6

3

0

High-throughput

0.347

High

276245

SEM7A
Semaphorin-7A

2

0

High-throughput

0.328

High

596755

DPEP1
Dipeptidase 1

2

0

High-throughput

0.328

High

850878

KI3L2
Killer cell immunoglobulin-like receptor 3DL2

2

0

High-throughput

0.328

High

1134784

OPCM
Opioid-binding protein/cell adhesion molecule

2

0

High-throughput

0.328

High

1238660

CC107
Coiled-coil domain-containing protein 107

2

0

High-throughput

0.328

High

1238670

RUSF1
RUS family member 1

2

0

High-throughput

0.328

High

1238708

HS3S2
Heparan sulfate glucosamine 3-O-sulfotransferase 2

2

0

High-throughput

0.328

High

208857

ZBT24
Zinc finger and BTB domain-containing protein 24

1

0

High-throughput

0.279

Low

463985

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

0

High-throughput

0.279

Low

534332

CD8B
T-cell surface glycoprotein CD8 beta chain

1

0

High-throughput

0.279

Low

854112

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.279

Low

914276

EFNA4
Ephrin-A4

1

0

High-throughput

0.279

Low

1206266

NHLC3
NHL repeat-containing protein 3

1

0

High-throughput

0.279

Low

1213616

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

0

High-throughput

0.279

Low

1238644

T179B
Transmembrane protein 179B

1

0

High-throughput

0.279

Low

1238647

CA210
Type III endosome membrane protein TEMP

1

0

High-throughput

0.279

Low

1238653

LRC17
Leucine-rich repeat-containing protein 17

1

0

High-throughput

0.279

Low

1238673

CREL1
Protein disulfide isomerase CRELD1

1

0

High-throughput

0.279

Low

1238684

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.279

Low

1238688

SPRNG
SREBP regulating gene protein

1

0

High-throughput

0.279

Low

1238693

ZC4H2
Zinc finger C4H2 domain-containing protein

1

0

High-throughput

0.279

Low

1238697

RPRM
Protein reprimo

1

0

High-throughput

0.279

Low

1238675

ODAD4
Outer dynein arm-docking complex subunit 4

1

0

High-throughput

0.269

Low

1238657

PJA1
E3 ubiquitin-protein ligase Praja-1

1

0

Small-scale

0.261

Low

588935

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

695722

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

768439

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

837669

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.249

Low

851776

NKX21
Homeobox protein Nkx-2.1

1

0

High-throughput

0.249

Low

965028

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.249

Low

979837

H4
Histone H4

1

0

High-throughput

0.249

Low

1163358

CAH9
Carbonic anhydrase 9

1

0

High-throughput

0.249

Low

1238641

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1238642

BT2A1
Butyrophilin subfamily 2 member A1

1

0

High-throughput

0.249

Low

1238643

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1238650

CXD3
Gap junction delta-3 protein

1

0

High-throughput

0.249

Low

1238665

S2546
Mitochondrial outer membrane protein SLC25A46

1

0

High-throughput

0.249

Low

1238687

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1238695

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.249

Low

1238699

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

330202

VENTX
Homeobox protein VENTX

1

0

High-throughput

0.232

Low

584108

FOSL2
Fos-related antigen 2

1

0

High-throughput

0.232

Low

587109

ITF2
Transcription factor 4

1

0

High-throughput

0.232

Low

598743

ANFB
Natriuretic peptides B

1

0

High-throughput

0.232

Low

653385

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.232

Low

1053012

VMAT2
Synaptic vesicular amine transporter

1

0

High-throughput

0.232

Low

1134112

NTCP
Hepatic sodium/bile acid cotransporter

1

0

High-throughput

0.232

Low

1238649

S35F2
Solute carrier family 35 member F2

1

0

High-throughput

0.232

Low

1238659

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

1

0

High-throughput

0.232

Low

1238669

MYEOV
Myeloma-overexpressed gene protein

1

0

High-throughput

0.232

Low

1238691

POPD2
Popeye domain-containing protein 2

1

0

High-throughput

0.232

Low

1238692

SO1B3
Solute carrier organic anion transporter family member 1B3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025