Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.893

The method score is based on:

Property Details
Experiments 10543959, 21183720, 30382094, 22939624
Identification Methods pull down, mass spectrometry studies of complexes, x ray scattering, molecular sieving, luminescence based mammalian interactome mapping
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HATPase_c_3~HATPase_c_3, HATPase_c_3~HSP90, HSP90~HSP90
Common GO terms GO:0001890 - placenta development
GO:0003723 - RNA binding
GO:0003725 - double-stranded RNA binding
GO:0005524 - ATP binding
GO:0005576 - extracellular region
and 66 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 724
Hs

1 724
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ At
+ Hs
+ Hs
+ Ce
+ Dm
+ Hs
+ Hs
+ Sp
+ Ca
+ Sc
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024