HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: RGS6 (P49758)
Regulator of G-protein signaling 6 (RGS6) (S914)
Gene: RGS6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	22939624
Identification Methods	luminescence based mammalian interactome mapping, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 472
+	Hs
		431654 HS90A_HUMAN (1-724): 0: 1072: 85.25		RGS6_HUMAN (1-472): 0: 692: 100.00
+	Hs
		437998 HS90B_HUMAN (1-724): 0: 1086: 100.00		RGS7_HUMAN (1-466): 0: 627: 72.16
+	Hs
		431657 HS90A_HUMAN (1-724): 0: 1072: 85.25		RGS7_HUMAN (1-466): 0: 627: 72.16
+	Hs
		277781 HS90B_HUMAN (1-724): 0: 1086: 100.00		RGS9_HUMAN (17-466): 0: 563: 37.75
+	Hs
		296585 HS90B_HUMAN (1-724): 0: 1086: 100.00		RGS11_HUMAN (22-464): 0: 540: 35.87
+	Hs
		296584 HS90A_HUMAN (1-724): 0: 1072: 85.25		RGS11_HUMAN (22-464): 0: 540: 35.87
+	Hs
		833683 Q6PK50_HUMAN (1-350): 0: 618: 99.71		RGS6_HUMAN (1-472): 0: 692: 100.00
+	Hs
		1118118 Q6PK50_HUMAN (1-350): 0: 618: 99.71		Q4TT70_HUMAN (22-464): 0: 540: 35.87
+	Hs
		1116919 Q6PK50_HUMAN (1-350): 0: 618: 99.71		Q4G1B2_HUMAN (60-466): 1.59e-176: 510: 38.54