HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: FBX6 (Q9NRD1)
F-box only protein 6 (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2)
Gene: FBXO6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	35043518, 22268729, 22939624
Identification Methods	affinity chromatography technology, luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006986 - response to unfolded protein
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 293
+	Hs
		432291 HS90A_HUMAN (1-724): 0: 1072: 85.25		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		438372 HS90B_HUMAN (1-724): 0: 1086: 100.00		FBX27_HUMAN (26-262): 8.01e-114: 331: 40.80
+	Hs
		432146 HS90A_HUMAN (1-724): 0: 1072: 85.25		FBX17_HUMAN (12-262): 4.9e-118: 342: 33.83
+	Hs
		538414 ENPL_HUMAN (3-693): 0: 917: 46.44		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		432080 HS90A_HUMAN (1-724): 0: 1072: 85.25		FBX27_HUMAN (26-262): 8.01e-114: 331: 40.80