HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: HECD1 (Q9ULT8)
E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)
Gene: HECTD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	33711283
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 2610
+	Hs
		125101 HS90B_HUMAN (1-724): 0: 1086: 100.00		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		125097 HS90A_HUMAN (1-724): 0: 1072: 85.25		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		438516 HS90B_HUMAN (1-724): 0: 1086: 100.00		WWP1_HUMAN (2328-2608): 5.47e-91: 321: 29.27
+	Hs
		432252 HS90A_HUMAN (1-724): 0: 1072: 85.25		WWP1_HUMAN (2328-2608): 5.47e-91: 321: 29.27
+	Sc
		543458 HSC82_YEAST (13-724): 0: 922: 60.22		UFD4_YEAST (2031-2610): 2.7e-129: 448: 28.16
+	Sc
		544112 HSC82_YEAST (13-724): 0: 922: 60.22		HUL5_YEAST (2050-2610): 8.38e-117: 397: 18.66
+	Sc
		366333 HSP82_YEAST (12-724): 0: 927: 61.26		RSP5_YEAST (2265-2608): 2.06e-105: 360: 20.86
+	Sc
		543785 HSC82_YEAST (13-724): 0: 922: 60.22		RSP5_YEAST (2265-2608): 2.06e-105: 360: 20.86
+	Hs
		438095 HS90B_HUMAN (1-724): 0: 1086: 100.00		UBE3A_HUMAN (2406-2607): 5.17e-25: 116: 34.95
+	Hs
		538246 ENPL_HUMAN (3-693): 0: 917: 46.44		UBE3C_HUMAN (2405-2610): 9.09e-23: 109: 32.37
+	Zm
		17433 A0A1D6GWE1_MAIZE (13-690): 0: 564: 47.81		A0A1D6MU59_MAIZE (2432-2604): 3.4e-19: 98.2: 33.90