HitPredict

Interactor 1: SRPRA (P08240)
Signal recognition particle receptor subunit alpha (SR-alpha) (Docking protein alpha) (DP-alpha)
Gene: SRPRA

Interactor 2: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005789 - endoplasmic reticulum membrane GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 638 Hs			1 192
+	Hs
		438679 SRPRA_HUMAN (1-638): 0: 783: 100.00		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		438730 SRPRA_HUMAN (1-638): 0: 783: 100.00		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		438743 SRPRA_HUMAN (1-638): 0: 783: 100.00		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Hs
		438731 SRPRA_HUMAN (1-638): 0: 783: 100.00		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		438733 SRPRA_HUMAN (1-638): 0: 783: 100.00		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		436124 SRPRA_HUMAN (1-638): 0: 783: 100.00		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45