Interactor 1: ELNE (P08246)
Neutrophil elastase (EC 3.4.21.37) (Bone marrow serine protease) (Elastase-2) (Human leukocyte elastase) (HLE) (Medullasin) (PMN elastase)
Gene: ELANE

Interactor 2: GRAB (P10144)
Granzyme B (EC 3.4.21.79) (C11) (CTLA-1) (Cathepsin G-like 1) (CTSGL1) (Cytotoxic T-lymphocyte proteinase 2) (Lymphocyte protease) (Fragmentin-2) (Granzyme-2) (Human lymphocyte protein) (HLP) (SECT) (T-cell serine protease 1-3E)
Gene: GZMB

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 9404514
Identification Methods x ray scattering
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Trypsin~Trypsin
Common GO terms GO:0004252 - serine-type endopeptidase activity
GO:0005576 - extracellular region
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0070269 - pyroptotic inflammatory response
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 267
Hs

1 247
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024