Protein: ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial (EC 1.2.4.1) (Pyruvate dehydrogenase complex component E1 alpha) (PDHE1-A)

Gene: ODPA, PDA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 197
UniProt ID: P16387

Gene Ontology (top 5):
GO:0004739 - pyruvate dehydrogenase (acetyl-transferring) activity
GO:0005739 - mitochondrion
GO:0006086 - acetyl-CoA biosynthetic process from pyruvate
GO:0007124 - pseudohyphal growth

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

520782

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

4

11

High-throughput

0.892

High

558593

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

4

15

High-throughput

0.892

High

558572

PDP2
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial

4

1

Small-scale

0.689

High

558597

PREP
Presequence protease, mitochondrial

3

12

High-throughput

0.662

High

558554

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

11

High-throughput

0.618

High

558558

ODO1
2-oxoglutarate dehydrogenase, mitochondrial

1

5

High-throughput

0.618

High

367527

EFTU
Elongation factor Tu, mitochondrial

2

2

High-throughput

0.584

High

452947

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

2

4

High-throughput

0.584

High

477859

HSP77
Import motor subunit, mitochondrial

2

4

High-throughput

0.584

High

558552

MDHM
Malate dehydrogenase, mitochondrial

2

4

High-throughput

0.584

High

558646

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.584

High

558585

HS104
Heat shock protein 104

3

4

High-throughput

0.578

High

558556

HSP60
Heat shock protein 60, mitochondrial

2

6

High-throughput

0.571

High

558606

MDJ1
DnaJ homolog 1, mitochondrial

2

3

High-throughput

0.571

High

558587

IMB3
Importin subunit beta-3

2

1

High-throughput

0.567

High

558659

BRE5
UBP3-associated protein BRE5

1

1

High-throughput

0.536

High

558637

PDK1
[Pyruvate dehydrogenase

1

9

Small-scale

0.515

High

558586

TPS2
Trehalose-phosphatase

1

0

High-throughput

0.513

High

434729

PBS2
MAP kinase kinase PBS2

1

2

High-throughput

0.489

High

558642

COPB2
Coatomer subunit beta'

1

1

High-throughput

0.489

High

443918

CYAA
Adenylate cyclase

1

0

High-throughput

0.479

High

558575

FEN1
Flap endonuclease 1

1

0

High-throughput

0.479

High

558665

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

0

High-throughput

0.479

High

341904

ATPB
ATP synthase subunit beta, mitochondrial

1

4

High-throughput

0.479

High

343083

THDH
Threonine dehydratase, mitochondrial

1

1

High-throughput

0.479

High

423746

ATPA
ATP synthase subunit alpha, mitochondrial

1

4

High-throughput

0.479

High

450591

ATPO
ATP synthase subunit 5, mitochondrial

1

1

High-throughput

0.479

High

489664

MPPB
Mitochondrial-processing peptidase subunit beta

1

11

High-throughput

0.479

High

498723

RT02
Small ribosomal subunit protein uS14m

1

1

High-throughput

0.479

High

516186

MPPA
Mitochondrial-processing peptidase subunit alpha

1

9

High-throughput

0.479

High

543125

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

546121

SYDM
Aspartate--tRNA ligase, mitochondrial

1

4

High-throughput

0.479

High

546133

SYKC
Lysine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

558551

ODPX
Pyruvate dehydrogenase complex protein X component, mitochondrial

1

12

High-throughput

0.479

High

558555

ACON
Aconitate hydratase, mitochondrial

1

3

High-throughput

0.479

High

558559

RT28
Small ribosomal subunit protein uS15m

1

1

High-throughput

0.479

High

558560

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

1

High-throughput

0.479

High

558562

AIM17
Probable oxidoreductase AIM17

1

1

High-throughput

0.479

High

558563

TOM40
Mitochondrial import receptor subunit TOM40

1

1

High-throughput

0.479

High

558565

SYNM
Asparagine--tRNA ligase, mitochondrial

1

3

High-throughput

0.479

High

558566

PRTD
Saccharolysin

1

2

High-throughput

0.479

High

558567

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

1

High-throughput

0.479

High

558573

CYPC
Peptidyl-prolyl cis-trans isomerase C, mitochondrial

1

1

High-throughput

0.479

High

558574

KAD3
GTP:AMP phosphotransferase, mitochondrial

1

5

High-throughput

0.479

High

558576

COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial

1

1

High-throughput

0.479

High

558577

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

3

High-throughput

0.479

High

558581

HIBCH
Small ribosomal subunit protein mS47

1

4

High-throughput

0.479

High

558583

RF1M
Peptide chain release factor 1, mitochondrial

1

8

High-throughput

0.479

High

558584

RM09
Large ribosomal subunit protein uL3m

1

1

High-throughput

0.479

High

558595

DLD1
D-lactate dehydrogenase [cytochrome] 1, mitochondrial

1

3

High-throughput

0.479

High

558598

RT04
Small ribosomal subunit protein uS2m

1

2

High-throughput

0.479

High

558602

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.479

High

558609

PMIP
Mitochondrial intermediate peptidase

1

2

High-throughput

0.479

High

558613

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.479

High

558615

ETR1
Enoyl-[acyl-carrier-protein] reductase, mitochondrial

1

5

High-throughput

0.479

High

558619

GRPE
GrpE protein homolog, mitochondrial

1

1

High-throughput

0.479

High

558622

YLF2
Obg-like ATPase homolog

1

3

High-throughput

0.479

High

558630

SYPM
Probable proline--tRNA ligase, mitochondrial

1

2

High-throughput

0.479

High

558632

ALDH5
Aldehyde dehydrogenase 5, mitochondrial

1

4

High-throughput

0.479

High

558645

ETFB
Probable electron transfer flavoprotein subunit beta

1

2

High-throughput

0.479

High

558647

DLD2
D-2-hydroxyglutarate--pyruvate transhydrogenase DLD2

1

3

High-throughput

0.479

High

558649

RT07
Small ribosomal subunit protein uS7m

1

1

High-throughput

0.479

High

558650

CAF17
Putative transferase CAF17, mitochondrial

1

1

High-throughput

0.479

High

558651

GCST
Aminomethyltransferase, mitochondrial

1

1

High-throughput

0.479

High

558654

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

1

3

High-throughput

0.479

High

558656

LYS4
Homoaconitase, mitochondrial

1

3

High-throughput

0.479

High

558661

RM22
Large ribosomal subunit protein uL22m

1

1

High-throughput

0.479

High

558662

FMP41
Uncharacterized mitochondrial hydrolase FMP41

1

1

High-throughput

0.479

High

558671

ISU1
Iron sulfur cluster assembly protein 1, mitochondrial

1

1

High-throughput

0.479

High

558673

RT17
Small ribosomal subunit protein uS17m

1

3

High-throughput

0.479

High

558680

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

4

High-throughput

0.479

High

558688

COQ10
Coenzyme Q-binding protein COQ10, mitochondrial

1

1

High-throughput

0.479

High

558693

YOR22
Probable phospholipase YOR022C, mitochondrial

1

2

High-throughput

0.479

High

558697

RM23
Large ribosomal subunit protein uL13m

1

2

High-throughput

0.479

High

558699

SMC6
Structural maintenance of chromosomes protein 6

1

2

High-throughput

0.479

High

558686

YP097
PX domain-containing protein YPR097W

1

0

Small-scale

0.460

High

141632

COQ4
Ubiquinone biosynthesis protein COQ4, mitochondrial

1

0

High-throughput

0.458

High

336710

SODM
Superoxide dismutase [Mn], mitochondrial

1

0

High-throughput

0.458

High

371009

CBP2
Cytochrome B pre-mRNA-processing protein 2

1

0

High-throughput

0.458

High

389363

HXKB
Hexokinase-2

1

0

High-throughput

0.458

High

410745

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.458

High

423571

ADH3
Alcohol dehydrogenase 3, mitochondrial

1

0

High-throughput

0.458

High

427169

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

0

High-throughput

0.458

High

482054

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

486127

ADH4
Alcohol dehydrogenase 4

1

0

High-throughput

0.458

High

520463

RM02
Large ribosomal subunit protein bL27m

1

0

High-throughput

0.458

High

558553

ATP10
Mitochondrial ATPase complex subunit ATP10

1

0

High-throughput

0.458

High

558557

RM33
Large ribosomal subunit protein uL30m

1

0

High-throughput

0.458

High

558561

RM20
Large ribosomal subunit protein mL58

1

0

High-throughput

0.458

High

558569

ILV6
Acetolactate synthase small subunit, mitochondrial

1

0

High-throughput

0.458

High

558570

IMG1
Large ribosomal subunit protein bL19m

1

0

High-throughput

0.458

High

558571

IMG2
Large ribosomal subunit protein mL49

1

0

High-throughput

0.458

High

558579

RT06
Small ribosomal subunit protein bS6m

1

0

High-throughput

0.458

High

558591

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

0

High-throughput

0.458

High

558596

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.458

High

558599

RM06
Large ribosomal subunit protein uL6m

1

0

High-throughput

0.458

High

558607

RM38
Large ribosomal subunit protein uL14m

1

0

High-throughput

0.458

High

558611

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.458

High

558612

RM24
Large ribosomal subunit protein bL28m

1

0

High-throughput

0.458

High

558614

RM16
Large ribosomal subunit protein uL16m

1

0

High-throughput

0.458

High

558616

PANB
3-methyl-2-oxobutanoate hydroxymethyltransferase

1

0

High-throughput

0.458

High

558621

PHS
Putative pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.458

High

558625

BCA1
Branched-chain-amino-acid aminotransferase, mitochondrial

1

0

High-throughput

0.458

High

558627

ILV3
Dihydroxy-acid dehydratase, mitochondrial

1

0

High-throughput

0.458

High

558631

PPOX
Protoporphyrinogen oxidase

1

0

High-throughput

0.458

High

558633

AIM9
Altered inheritance of mitochondria protein 9, mitochondrial

1

0

High-throughput

0.458

High

558635

MMF1
Protein MMF1, mitochondrial

1

0

High-throughput

0.458

High

558640

RN49
Large ribosomal subunit protein bL21m

1

0

High-throughput

0.458

High

558641

COQ7
5-demethoxyubiquinone hydroxylase, mitochondrial

1

0

High-throughput

0.458

High

558644

RT18
Small ribosomal subunit protein uS11m

1

0

High-throughput

0.458

High

558655

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.458

High

558657

ALAM
Probable alanine aminotransferase, mitochondrial

1

0

High-throughput

0.458

High

558658

SUCA
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

558664

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

558667

ABF2
ARS-binding factor 2, mitochondrial

1

0

High-throughput

0.458

High

558668

GLRX5
Monothiol glutaredoxin-5, mitochondrial

1

0

High-throughput

0.458

High

558669

RT51
Small ribosomal subunit protein bS1m

1

0

High-throughput

0.458

High

558670

ESP1
Separin

1

0

High-throughput

0.458

High

558672

RT10
Small ribosomal subunit protein uS10m

1

0

High-throughput

0.458

High

558676

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.458

High

558678

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

558679

COQ11
MIOREX complex component 2

1

0

High-throughput

0.458

High

558681

RRG8
Required for respiratory growth protein 8, mitochondrial

1

0

High-throughput

0.458

High

558684

MHR1
Large ribosomal subunit protein mL67

1

0

High-throughput

0.458

High

558685

RM35
Large ribosomal subunit protein mL38

1

0

High-throughput

0.458

High

558687

POS5
NADH kinase POS5, mitochondrial

1

0

High-throughput

0.458

High

558689

ETFD
Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial

1

0

High-throughput

0.458

High

558691

LEU9
2-isopropylmalate synthase 2, mitochondrial

1

0

High-throughput

0.458

High

558692

RRG1
Required for respiratory growth protein 1, mitochondrial

1

0

High-throughput

0.458

High

477105

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

2

High-throughput

0.457

High

439620

SPS1
Sporulation-specific protein 1

1

3

High-throughput

0.457

High

558588

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

1

2

High-throughput

0.457

High

558592

CDC12
Cell division control protein 12

1

1

High-throughput

0.457

High

558626

TEM1
Protein TEM1

1

5

High-throughput

0.457

High

424326

PYR1
Multifunctional protein URA2

1

2

High-throughput

0.445

High

365730

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.437

High

413278

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

481465

RS11B
Small ribosomal subunit protein uS17B

1

3

High-throughput

0.437

High

558564

SIS1
Protein SIS1

1

3

High-throughput

0.437

High

558568

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.437

High

558600

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.437

High

558601

PRS6A
26S proteasome regulatory subunit 6A

1

4

High-throughput

0.437

High

558604

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.437

High

558608

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.437

High

558610

CENPA
Histone H3-like centromeric protein CSE4

1

4

High-throughput

0.437

High

558674

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.437

High

558696

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.437

High

558698

CMR1
DNA damage-binding protein CMR1

1

1

High-throughput

0.437

High

510152

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.407

High

558634

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.407

High

558594

SMI1
Cell wall assembly regulator SMI1

2

0

Small-scale

0.307

High

341643

ARGI
Arginase

1

0

High-throughput

0.261

Low

419295

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.261

Low

420429

RAD10
DNA repair protein RAD10

1

0

High-throughput

0.261

Low

533928

INO4
Protein INO4

1

0

High-throughput

0.261

Low

558578

YJU2
Splicing factor YJU2

1

0

High-throughput

0.261

Low

558590

KNS1
Dual specificity protein kinase KNS1

1

0

High-throughput

0.261

Low

558618

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.261

Low

558620

DBP8
ATP-dependent RNA helicase DBP8

1

0

High-throughput

0.261

Low

558663

IGO1
mRNA stability protein IGO1

1

0

High-throughput

0.261

Low

558638

MPH1
ATP-dependent DNA helicase MPH1

1

0

Small-scale

0.251

Low

252688

MRP10
Small ribosomal subunit protein mS37

1

0

High-throughput

0.249

Low

357857

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

399317

RLA0
Large ribosomal subunit protein uL10

1

0

Small-scale

0.249

Low

406749

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.249

Low

407697

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.249

Low

470835

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

471994

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

480452

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

524142

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

557851

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.249

Low

558580

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.249

Low

558582

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

558589

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

558603

SPC29
Spindle pole component 29

1

0

High-throughput

0.249

Low

558605

IF4B
Eukaryotic translation initiation factor 4B

1

0

High-throughput

0.249

Low

558617

RRN10
RNA polymerase I-specific transcription initiation factor RRN10

1

0

High-throughput

0.249

Low

558623

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.249

Low

558624

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.249

Low

558629

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

558636

NAGS
Amino-acid acetyltransferase, mitochondrial

1

0

High-throughput

0.249

Low

558639

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

558648

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

558652

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

558653

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

558660

GIS2
Zinc finger protein GIS2

1

0

High-throughput

0.249

Low

558666

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

558675

ESC1
Silent chromatin protein ESC1

1

0

High-throughput

0.249

Low

558677

EIF3J
Eukaryotic translation initiation factor 3 subunit J

1

0

High-throughput

0.249

Low

558682

SEC10
Exocyst complex component SEC10

1

0

Small-scale

0.249

Low

558683

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

558690

NIP7
60S ribosome subunit biogenesis protein NIP7

1

0

High-throughput

0.249

Low

558695

ARP8
Actin-like protein ARP8

1

0

High-throughput

0.249

Low

540017

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.232

Low

558628

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.232

Low

558643

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

558694

MAM3
Protein MAM3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024