HitPredict

Interactor 1: AT1B1 (P08251)
Sodium/potassium-transporting ATPase subunit beta-1 (Sodium/potassium-dependent ATPase subunit beta-1)
Gene: ATP1B1

Interactor 2: AT1A1 (P09572)
Sodium/potassium-transporting ATPase subunit alpha-1 (Na(+)/K(+) ATPase alpha-1 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-1)
Gene: ATP1A1

Species: Gallus gallus

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.42	1.00	0.653

Property	Details
Experiments	9139681
Identification Methods	two hybrid, biochemical
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cation_ATPase_C~Na_K-ATPase
Common GO terms	GO:0005890 - sodium:potassium-exchanging ATPase complex GO:0006883 - intracellular sodium ion homeostasis GO:0030007 - intracellular potassium ion homeostasis GO:0036376 - sodium ion export across plasma membrane GO:1990573 - potassium ion import across plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 305 Gg			1 1021
+	Ss
		393404 AT1B1_PIG (1-304): 4.25e-145: 411: 70.72		AT1A1_PIG (1-1021): 0: 1109: 92.75
+	Hs
		392975 AT1B1_HUMAN (1-304): 1.06e-146: 416: 71.05		AT1A1_HUMAN (1-1021): 0: 1099: 92.38
+	Mm
		534638 AT1B1_MOUSE (1-304): 1.31e-143: 408: 70.16		AT1A1_MOUSE (1-1021): 0: 1103: 92.28
+	Oc
		1341483 AT1B1_RABIT (1-304): 6.66e-145: 411: 70.40		AT1A1_RABIT (1-1021): 0: 1098: 93.35
+	Hs
		393412 AT1B1_HUMAN (1-304): 1.06e-146: 416: 71.05		AT1A3_HUMAN (25-1021): 0: 1060: 86.86
+	Hs
		530820 AT1B2_HUMAN (8-305): 1.53e-122: 354: 38.00		AT1A3_HUMAN (25-1021): 0: 1060: 86.86
+	Hs
		393119 AT1B3_HUMAN (7-304): 1.54e-105: 310: 37.62		AT1A1_HUMAN (1-1021): 0: 1099: 92.38
+	Hs
		393416 AT1B1_HUMAN (1-304): 1.06e-146: 416: 71.05		ATP4A_HUMAN (1-1021): 0: 970: 62.43
+	Hs
		393427 AT1B1_HUMAN (1-304): 1.06e-146: 416: 71.05		AT12A_HUMAN (3-1021): 0: 959: 64.61
+	Hs
		530858 AT1B3_HUMAN (7-304): 1.54e-105: 310: 37.62		AT1A3_HUMAN (25-1021): 0: 1060: 86.86
+	Dm
		530286 ATPB2_DROME (11-303): 5.97e-98: 293: 26.27		ATNA_DROME (8-1021): 0: 1024: 73.77
+	Hs
		1045040 AT1B4_HUMAN (9-304): 5.21e-111: 327: 34.65		AT1A4_HUMAN (17-1021): 0: 987: 78.01
+	Oc
		577714 ATP4B_RABIT (8-304): 5.5e-113: 330: 32.23		ATP4A_RABIT (1-1021): 0: 968: 62.33
+	Hs
		594721 ATP4B_HUMAN (8-304): 2.11e-111: 325: 30.23		ATP4A_HUMAN (1-1021): 0: 970: 62.43
+	Ss
		577082 ATP4B_PIG (8-304): 6.15e-111: 324: 29.57		ATP4A_PIG (1-1021): 0: 961: 62.33
+	Hs
		871888 AT1B3_HUMAN (7-304): 1.54e-105: 310: 37.62		AT12A_HUMAN (3-1021): 0: 959: 64.61