HitPredict

Interactor 1: MMP2 (P08253)
72 kDa type IV collagenase (EC 3.4.24.24) (72 kDa gelatinase) (Gelatinase A) (Matrix metalloproteinase-2) (MMP-2) (TBE-1) [Cleaved into: PEX]
Gene: MMP2

Interactor 2: TIMP4 (Q99727)
Metalloproteinase inhibitor 4 (Tissue inhibitor of metalloproteinases 4) (TIMP-4)
Gene: TIMP4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.845

The method score is based on:

Property Details
Experiments 9182583, 12374789, 12475252
Identification Methods pull down, enzymatic study
Interaction Type direct interaction, enzymatic reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Hemopexin~TIMP, Peptidase_M10~TIMP
Common GO terms GO:0005615 - extracellular space
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 660
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024