HitPredict

Interactor 1: FYN (P06241)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)
Gene: FYN

Interactor 2: FKBP5 (Q13451)
Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase)
Gene: FKBP5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	FKBP_C~PK_Tyr_Ser-Thr
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 537 Hs			1 457
+	Hs
		463084 YES_HUMAN (1-537): 0: 592: 71.61		FKBP5_HUMAN (1-457): 6.1e-146: 426: 100.00
+	Hs
		486691 FGR_HUMAN (1-536): 0: 582: 69.82		FKBP5_HUMAN (1-457): 6.1e-146: 426: 100.00
+	Hs
		440035 LCK_HUMAN (40-535): 0: 552: 57.40		FKBP4_HUMAN (1-456): 4.32e-138: 406: 53.93
+	Hs
		902833 BLK_HUMAN (28-532): 1.62e-179: 516: 56.72		FKBP5_HUMAN (1-457): 6.1e-146: 426: 100.00
+	Hs
		1106069 SRMS_HUMAN (50-528): 1.33e-151: 444: 38.80		FKBP5_HUMAN (1-457): 6.1e-146: 426: 100.00
+	Hs
		124715 FYN_HUMAN (1-537): 0: 644: 100.00		AIP_HUMAN (144-414): 3.07e-49: 172: 16.72
+	Hs
		124727 SRC_HUMAN (1-537): 0: 598: 68.21		AIP_HUMAN (144-414): 3.07e-49: 172: 16.72
+	Hs
		124719 YES_HUMAN (1-537): 0: 592: 71.61		AIP_HUMAN (144-414): 3.07e-49: 172: 16.72
+	Hs
		124723 FGR_HUMAN (1-536): 0: 582: 69.82		AIP_HUMAN (144-414): 3.07e-49: 172: 16.72
+	Hs
		440047 LCK_HUMAN (40-535): 0: 552: 57.40		PPID_HUMAN (249-414): 4.13e-51: 178: 24.55
+	Hs
		124714 LCK_HUMAN (40-535): 0: 552: 57.40		AIP_HUMAN (144-414): 3.07e-49: 172: 16.72
+	Hs
		124754 BLK_HUMAN (28-532): 1.62e-179: 516: 56.72		AIP_HUMAN (144-414): 3.07e-49: 172: 16.72
+	Hs
		439971 LCK_HUMAN (40-535): 0: 552: 57.40		STIP1_HUMAN (265-457): 4.42e-23: 103: 17.62