HitPredict

Interactor 1: PTPRC (P08575)
Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (L-CA) (T200) (CD antigen CD45)
Gene: PTPRC

Interactor 2: PGFRB (P09619)
Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)
Gene: PDGFRB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 19167335
Identification Methods phosphatase assay
Interaction Type dephosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains fn3~ig, Ig_3~fn3, PK_Tyr_Ser-Thr~fn3, PK_Tyr_Ser-Thr~Y_phosphatase
Common GO terms GO:0005102 - signaling receptor binding
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0016020 - membrane
GO:0019901 - protein kinase binding
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024