Protein: KAPC
cAMP-dependent protein kinase type 3 (PKA 3) (EC 2.7.11.11)

Gene: KAPC, TPK3
Organism: Saccharomyces cerevisiae S288C
Interactions: 126
UniProt ID: P05986

Gene Ontology (top 5):
GO:0000932 - P-body
GO:0004672 - protein kinase activity
GO:0004691 - cAMP-dependent protein kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

437863

KAPR
cAMP-dependent protein kinase regulatory subunit

11

20

Small-scale

0.977

High

437859

KAPB
cAMP-dependent protein kinase type 2

8

16

Small-scale

0.968

High

437858

KAPA
cAMP-dependent protein kinase type 1

4

16

High-throughput

0.899

High

437954

PKH1
Serine/threonine-protein kinase PKH1

2

16

Small-scale

0.825

High

437946

JJJ1
J protein JJJ1

2

15

High-throughput

0.799

High

437882

KC11
Casein kinase I homolog 1

1

16

High-throughput

0.691

High

437904

YPT7
Ypt/Rab-type GTPase YPT7

1

1

High-throughput

0.691

High

437909

YPT53
GTP-binding protein YPT53

1

3

High-throughput

0.691

High

437855

KAPC
cAMP-dependent protein kinase type 3

1

15

High-throughput

0.656

High

391981

HSP82
ATP-dependent molecular chaperone HSP82

1

20

High-throughput

0.647

High

437878

KIN3
Serine/threonine-protein kinase KIN3

1

19

High-throughput

0.647

High

437880

KCC2
Calcium/calmodulin-dependent protein kinase II

1

6

High-throughput

0.647

High

437887

KCC1
Calcium/calmodulin-dependent protein kinase I

1

9

High-throughput

0.647

High

437888

CDC15
Cell division control protein 15

1

14

High-throughput

0.647

High

437896

HOG1
Mitogen-activated protein kinase HOG1

1

20

High-throughput

0.647

High

437898

ZUO1
Zuotin

1

19

High-throughput

0.647

High

437906

WHI3
Protein WHI3

1

2

Small-scale

0.647

High

437908

NNK1
Nitrogen network kinase 1

1

12

High-throughput

0.647

High

437914

AKL1
Serine/threonine-protein kinase AKL1

1

14

High-throughput

0.647

High

437917

KSP1
Serine/threonine-protein kinase KSP1

1

17

High-throughput

0.647

High

437936

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

12

High-throughput

0.647

High

437940

ATG1
Serine/threonine-protein kinase ATG1

1

17

High-throughput

0.647

High

437899

RPN2
26S proteasome regulatory subunit RPN2

1

3

High-throughput

0.646

High

437860

PHSG
Glycogen phosphorylase

2

2

High-throughput

0.628

High

437948

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

20

High-throughput

0.621

High

376254

YPT1
GTP-binding protein YPT1

1

1

Small-scale

0.618

High

437967

PCL9
PHO85 cyclin-9

1

0

High-throughput

0.614

High

437870

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

5

High-throughput

0.536

High

437943

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

2

High-throughput

0.536

High

437924

GPB2
Guanine nucleotide-binding protein subunit beta 2

1

2

Small-scale

0.527

High

437861

PUR2
Bifunctional purine biosynthetic protein ADE5,7 [Includes: Phosphoribosylamine--glycine ligase

1

0

High-throughput

0.513

High

437916

YHJ3
Uncharacterized protein YHR033W

1

0

High-throughput

0.513

High

383048

RLA4
Large ribosomal subunit protein P2B

1

1

High-throughput

0.501

High

437856

NOT2
General negative regulator of transcription subunit 2

1

1

High-throughput

0.501

High

437857

PDC1
Pyruvate decarboxylase isozyme 1

1

1

High-throughput

0.501

High

437864

RS19A
Small ribosomal subunit protein eS19A

1

3

High-throughput

0.501

High

437867

MALX2
Oligo-1,6-glucosidase IMA3

1

2

High-throughput

0.501

High

437868

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.501

High

437869

DHAS
Aspartate-semialdehyde dehydrogenase

1

1

High-throughput

0.501

High

437874

IRA2
Inhibitory regulator protein IRA2

1

9

Small-scale

0.501

High

437879

TRX1
Thioredoxin-1

1

1

High-throughput

0.501

High

437885

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

3

Small-scale

0.501

High

437889

BUD14
Bud site selection protein 14

1

1

High-throughput

0.501

High

437892

ZIP1
Synaptonemal complex protein ZIP1

1

12

High-throughput

0.501

High

437893

TREA
Cytosolic neutral trehalase

1

2

Small-scale

0.501

High

437894

APE2
Aminopeptidase 2, mitochondrial

1

2

High-throughput

0.501

High

437900

PAH1
Phosphatidic acid phosphohydrolase 1

1

2

Small-scale

0.501

High

437902

RGT1
Glucose transport transcription regulator RGT1

1

2

Small-scale

0.501

High

437910

SIS2
Phosphopantothenoylcysteine decarboxylase subunit SIS2

1

1

High-throughput

0.501

High

437913

PUR92
Bifunctional purine biosynthesis protein ADE17 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

1

2

High-throughput

0.501

High

437915

MAK5
ATP-dependent RNA helicase MAK5

1

11

High-throughput

0.501

High

437918

KEL1
Kelch repeat-containing protein 1

1

4

High-throughput

0.501

High

437920

RGD3
Rho-GTPase-activating protein RGD3

1

1

High-throughput

0.501

High

437929

YJH0
Inactive deaminase YJL070C

1

2

High-throughput

0.501

High

437930

INP51
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase INP51

1

1

High-throughput

0.501

High

437932

ELP2
Elongator complex protein 2

1

5

High-throughput

0.501

High

437933

IGD1
Inhibitor of glycogen debranching 1

1

2

High-throughput

0.501

High

437935

DENR
Translation machinery-associated protein 22

1

1

High-throughput

0.501

High

437938

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

5

High-throughput

0.501

High

437939

STR3
Cystathionine beta-lyase

1

1

High-throughput

0.501

High

437942

PDK2
[Pyruvate dehydrogenase

1

7

High-throughput

0.501

High

437952

SPP1
COMPASS component SPP1

1

1

High-throughput

0.501

High

437953

ADD37
Alpha1-proteinase inhibitor-degradation deficient protein 37

1

2

High-throughput

0.501

High

437955

SNX41
Sorting nexin-41

1

3

High-throughput

0.501

High

437960

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase

1

1

High-throughput

0.501

High

437961

CMS1
Protein CMS1

1

1

High-throughput

0.501

High

437964

NOP53
Ribosome biogenesis protein NOP53

1

2

High-throughput

0.501

High

437966

BAG7
Rho-GTPase-activating protein BAG7

1

5

High-throughput

0.501

High

394093

EF1A
Elongation factor 1-alpha

1

5

High-throughput

0.500

High

404995

LEU3
3-isopropylmalate dehydrogenase

1

3

High-throughput

0.500

High

416331

HXKA
Hexokinase-1

1

4

High-throughput

0.500

High

437862

PYR1
Multifunctional protein URA2

1

7

High-throughput

0.500

High

437866

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

4

High-throughput

0.500

High

437871

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

5

High-throughput

0.500

High

437886

CDC48
Cell division control protein 48

1

5

High-throughput

0.500

High

437950

PRS8
26S proteasome regulatory subunit 8 homolog

1

8

High-throughput

0.500

High

437927

GIP2
GLC7-interacting protein 2

1

2

High-throughput

0.489

High

437931

COPB2
Coatomer subunit beta'

1

5

High-throughput

0.489

High

437901

PP12
Serine/threonine-protein phosphatase PP1-2

1

5

Small-scale

0.481

High

437865

SYSC
Serine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.480

High

437875

DCAM
S-adenosylmethionine decarboxylase proenzyme

1

0

High-throughput

0.480

High

437876

CCA1
CCA tRNA nucleotidyltransferase, mitochondrial

1

0

High-throughput

0.480

High

437877

OPI1
Transcriptional repressor OPI1

1

0

High-throughput

0.480

High

437881

APN1
Apurinic-apyrimidinic endonuclease 1

1

0

High-throughput

0.480

High

437891

MLS1
Malate synthase 1

1

0

High-throughput

0.480

High

437911

YKC3
Uncharacterized protein YKL023W

1

0

High-throughput

0.480

High

437921

ADY1
Prospore formation at selected spindle poles protein 1

1

0

High-throughput

0.480

High

437947

DOS2
Protein DOS2

1

0

High-throughput

0.480

High

437965

ATG29
Autophagy-related protein 29

1

0

High-throughput

0.480

High

437970

DDP1
Diphosphoinositol polyphosphate phosphohydrolase DDP1

1

0

High-throughput

0.480

High

437890

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

437925

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

High-throughput

0.479

High

437937

JHD2
Histone demethylase JHD2

1

4

Small-scale

0.479

High

437957

PDS5
Sister chromatid cohesion protein PDS5

1

1

High-throughput

0.479

High

394008

EFTU
Elongation factor Tu, mitochondrial

1

9

High-throughput

0.457

High

427515

RLA1
Large ribosomal subunit protein P1A

1

1

High-throughput

0.457

High

437873

GAP1
General amino-acid permease GAP1

1

4

Small-scale

0.457

High

437883

MBR1
Mitochondrial biogenesis regulation protein 1

1

2

High-throughput

0.457

High

437897

ISF1
Increasing suppression factor 1

1

2

High-throughput

0.457

High

437903

SSO1
Protein SSO1

1

2

High-throughput

0.457

High

437907

MNR2
Manganese resistance protein MNR2

1

4

High-throughput

0.457

High

437912

RM07
Large ribosomal subunit protein uL5m

1

2

High-throughput

0.457

High

437919

MTG2
GTPase MTG2, mitochondrial

1

5

High-throughput

0.457

High

437926

SIT1
Siderophore iron transporter 1

1

1

High-throughput

0.457

High

437928

VPS27
Vacuolar protein sorting-associated protein 27

1

2

High-throughput

0.457

High

437934

AVT1
Vacuolar amino acid transporter 1

1

4

High-throughput

0.457

High

437944

YIF1
Protein transport protein YIF1

1

3

High-throughput

0.457

High

437945

CWC25
Pre-mRNA-splicing factor CWC25

1

1

High-throughput

0.457

High

437951

LCL1
Long chronological lifespan protein 1

1

1

High-throughput

0.457

High

437959

RGA2
Rho-type GTPase-activating protein 2

1

5

High-throughput

0.457

High

437884

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

2

High-throughput

0.457

High

437872

DAP2
Dipeptidyl aminopeptidase B

1

0

High-throughput

0.261

Low

437895

ERG24
Delta(14)-sterol reductase ERG24

1

0

High-throughput

0.261

Low

437905

RE104
Meiotic recombination protein REC104

1

0

High-throughput

0.261

Low

437922

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

High-throughput

0.261

Low

437923

PNT1
Pentamidine resistance factor, mitochondrial

1

0

High-throughput

0.261

Low

437941

MPS2
Monopolar spindle protein 2

1

0

High-throughput

0.261

Low

437949

MRS2
Magnesium transporter MRS2, mitochondrial

1

0

High-throughput

0.261

Low

437956

UBX2
UBX domain-containing protein 2

1

0

High-throughput

0.261

Low

437958

ECM7
Protein ECM7

1

0

High-throughput

0.261

Low

437962

VAM10
Vacuolar morphogenesis protein 10

1

0

High-throughput

0.261

Low

437963

ALG6
Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase

1

0

High-throughput

0.261

Low

437968

SEC39
Protein transport protein SEC39

1

0

High-throughput

0.261

Low

437969

YB298
Uncharacterized protein YBR298C-A

1

0

High-throughput

0.261

Low

150108

YH1A
Putative uncharacterized protein YHR214W-A

1

0

High-throughput

0.261

Low


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Last updated: 11Aug2025