HitPredict

Interactor 1: PTPRC (P08575)
Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (L-CA) (T200) (CD antigen CD45)
Gene: PTPRC

Interactor 2: GHR (P10912)
Growth hormone receptor (GH receptor) (Somatotropin receptor) [Cleaved into: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)]
Gene: GHR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 19167335
Identification Methods phosphatase assay
Interaction Type dephosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains EpoR_lig-bind~fn3, fn3~fn3
Common GO terms GO:0005886 - plasma membrane
GO:0009897 - external side of plasma membrane
GO:0009986 - cell surface
GO:0016020 - membrane
GO:0019901 - protein kinase binding
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Last updated: 15 Jul 2024