Protein: GATA1
Erythroid transcription factor (Eryf1) (GATA-binding factor 1) (GATA-1) (GF-1) (NF-E1 DNA-binding protein)

Gene: GATA1
Organism: Homo sapiens
Interactions: 176
UniProt ID: P15976

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

590432

TRIP6
Thyroid receptor-interacting protein 6

5

0

High-throughput

0.887

High

590383

RBTN2
Rhombotin-2

1

11

Small-scale

0.740

High

590425

FHL3
Four and a half LIM domains protein 3

1

1

High-throughput

0.723

High

225530

AAKB2
5'-AMP-activated protein kinase subunit beta-2

5

0

High-throughput

0.697

High

590404

FLI1
Friend leukemia integration 1 transcription factor

3

9

Small-scale

0.683

High

590393

HXA1
Homeobox protein Hox-A1

3

14

High-throughput

0.675

High

590491

DHX36
ATP-dependent DNA/RNA helicase DHX36

3

1

High-throughput

0.667

High

590441

TENS2
Tensin-2

3

1

High-throughput

0.661

High

590482

MDFI
MyoD family inhibitor

2

1

High-throughput

0.651

High

590379

SPI1
Transcription factor PU.1

3

14

Small-scale

0.646

High

415327

HSPB1
Heat shock protein beta-1

2

3

Small-scale

0.631

High

590387

AKT1
RAC-alpha serine/threonine-protein kinase

2

2

Small-scale

0.619

High

590454

PIAS4
E3 SUMO-protein ligase PIAS4

2

2

Small-scale

0.611

High

590465

FOG2
Zinc finger protein ZFPM2

2

11

Small-scale

0.606

High

590403

PITX1
Pituitary homeobox 1

2

4

High-throughput

0.606

High

590414

TLE5
TLE family member 5

2

10

High-throughput

0.606

High

590442

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

7

High-throughput

0.606

High

590417

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

2

3

Small-scale

0.595

High

590476

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

2

7

Small-scale

0.595

High

590378

TAL1
T-cell acute lymphocytic leukemia protein 1

2

9

Small-scale

0.586

High

590416

EP300
Histone acetyltransferase p300

2

20

Small-scale

0.584

High

590434

NF2L2
Nuclear factor erythroid 2-related factor 2

1

3

Small-scale

0.582

High

590431

MED1
Mediator of RNA polymerase II transcription subunit 1

1

13

Small-scale

0.581

High

590418

MKRN3
E3 ubiquitin-protein ligase makorin-3

2

0

High-throughput

0.580

High

590464

TEKT4
Tektin-4

2

0

High-throughput

0.580

High

590486

DGC6L
Protein DGCR6L

2

0

High-throughput

0.580

High

590499

PLS4
Phospholipid scramblase 4

2

0

High-throughput

0.580

High

590503

FANCL
E3 ubiquitin-protein ligase FANCL

2

0

High-throughput

0.580

High

590472

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

4

Small-scale

0.578

High

188163

HDAC3
Histone deacetylase 3

1

15

Small-scale

0.561

High

590385

PML
Protein PML

1

9

Small-scale

0.561

High

590398

HDAC4
Histone deacetylase 4

1

20

Small-scale

0.561

High

590509

HDAC5
Histone deacetylase 5

1

20

Small-scale

0.561

High

292809

GRAP2
GRB2-related adapter protein 2

1

1

High-throughput

0.560

High

300099

GLRX3
Glutaredoxin-3

1

1

High-throughput

0.560

High

590419

TRAF1
TNF receptor-associated factor 1

1

1

High-throughput

0.560

High

590473

RBPMS
RNA-binding protein with multiple splicing

1

1

High-throughput

0.560

High

590488

KR411
Keratin-associated protein 4-11

2

7

High-throughput

0.553

High

590489

KRA45
Keratin-associated protein 4-5

2

7

High-throughput

0.553

High

590480

HEXI2
Protein HEXIM2

1

0

High-throughput

0.549

High

182014

ZBT22
Zinc finger and BTB domain-containing protein 22

1

7

High-throughput

0.541

High

590420

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

2

High-throughput

0.541

High

590426

TRI29
Tripartite motif-containing protein 29

1

2

High-throughput

0.541

High

590427

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

1

High-throughput

0.541

High

590445

RAI1
Retinoic acid-induced protein 1

1

7

High-throughput

0.541

High

185152

FANCG
Fanconi anemia group G protein

1

0

High-throughput

0.536

High

590390

BCL6
B-cell lymphoma 6 protein

1

0

High-throughput

0.536

High

590481

PP16B
Protein phosphatase 1 regulatory inhibitor subunit 16B

1

0

High-throughput

0.536

High

239534

MED14
Mediator of RNA polymerase II transcription subunit 14

1

5

Small-scale

0.536

High

590397

HSP72
Heat shock-related 70 kDa protein 2

1

2

High-throughput

0.536

High

590485

HEMGN
Hemogen

1

0

Small-scale

0.529

High

590391

CASP3
Caspase-3

1

0

Small-scale

0.527

High

590461

RIN3
Ras and Rab interactor 3

2

2

High-throughput

0.526

High

590483

LZTS2
Leucine zipper putative tumor suppressor 2

1

1

High-throughput

0.523

High

590487

KRA92
Keratin-associated protein 9-2

1

6

High-throughput

0.523

High

590490

KRA32
Keratin-associated protein 3-2

1

1

High-throughput

0.523

High

167492

TX1B3
Tax1-binding protein 3

1

0

High-throughput

0.518

High

590430

TAF7
Transcription initiation factor TFIID subunit 7

1

0

High-throughput

0.518

High

590453

ZZZ3
ZZ-type zinc finger-containing protein 3

1

0

High-throughput

0.518

High

590433

CEBPE
CCAAT/enhancer-binding protein epsilon

1

4

Small-scale

0.515

High

590450

FOG1
Zinc finger protein ZFPM1

1

11

Small-scale

0.515

High

167223

KLF11
Krueppel-like factor 11

1

15

High-throughput

0.515

High

301329

WFS1
Wolframin

1

1

High-throughput

0.515

High

384361

CRYAA
Alpha-crystallin A chain

1

3

High-throughput

0.515

High

590380

FGFR3
Fibroblast growth factor receptor 3

1

2

High-throughput

0.515

High

590392

BAG6
Large proline-rich protein BAG6

1

9

High-throughput

0.515

High

590447

Q86V38
Atrophin 1

1

7

High-throughput

0.515

High

590470

KLK6
Kallikrein-6

1

1

High-throughput

0.515

High

590511

RNF11
RING finger protein 11

1

1

High-throughput

0.515

High

590502

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

Small-scale

0.513

High

590415

GOGA2
Golgin subfamily A member 2

1

1

High-throughput

0.512

High

590436

MK06
Mitogen-activated protein kinase 6

1

7

High-throughput

0.508

High

154624

ARI1A
AT-rich interactive domain-containing protein 1A

1

18

Small-scale

0.501

High

464789

SP1
Transcription factor Sp1

1

10

Small-scale

0.501

High

590396

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

20

Small-scale

0.501

High

590405

SPIB
Transcription factor Spi-B

1

15

Small-scale

0.501

High

590460

SMRC2
SWI/SNF complex subunit SMARCC2

1

20

Small-scale

0.501

High

590469

CBP
CREB-binding protein

1

20

Small-scale

0.501

High

590471

SMRC1
SWI/SNF complex subunit SMARCC1

1

14

Small-scale

0.501

High

590474

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

12

Small-scale

0.501

High

590507

DNM3L
DNA

1

2

Small-scale

0.501

High

532339

CH60
60 kDa heat shock protein, mitochondrial

1

3

High-throughput

0.500

High

590381

CCNC
Cyclin-C

1

1

Small-scale

0.500

High

590389

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.500

High

590423

MED21
Mediator of RNA polymerase II transcription subunit 21

1

1

Small-scale

0.500

High

590510

MED16
Mediator of RNA polymerase II transcription subunit 16

1

2

Small-scale

0.500

High

590448

ZDH17
Palmitoyltransferase ZDHHC17

1

4

High-throughput

0.494

High

590446

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

227355

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.484

High

590496

SRA1
Steroid receptor RNA activator 1

1

0

Small-scale

0.480

High

48900

MED19
Mediator of RNA polymerase II transcription subunit 19

1

0

Small-scale

0.479

High

590401

PSME3
Proteasome activator complex subunit 3

1

0

High-throughput

0.479

High

590494

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

Small-scale

0.479

High

138968

BCL9
B-cell CLL/lymphoma 9 protein

1

15

High-throughput

0.479

High

161406

KMT2D
Histone-lysine N-methyltransferase 2D

1

16

High-throughput

0.479

High

174306

ZN609
Zinc finger protein 609

1

6

High-throughput

0.479

High

182905

NKRF
NF-kappa-B-repressing factor

1

1

High-throughput

0.479

High

194506

KDM6A
Lysine-specific demethylase 6A

1

7

High-throughput

0.479

High

228959

AKAP8
A-kinase anchor protein 8

1

2

High-throughput

0.479

High

261364

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

10

High-throughput

0.479

High

280487

PR40A
Pre-mRNA-processing factor 40 homolog A

1

4

High-throughput

0.479

High

321818

PCF11
Pre-mRNA cleavage complex 2 protein Pcf11

1

3

High-throughput

0.479

High

340726

CPSF4
Cleavage and polyadenylation specificity factor subunit 4

1

1

High-throughput

0.479

High

442575

RB
Retinoblastoma-associated protein

1

1

Small-scale

0.479

High

590388

HSP74
Heat shock 70 kDa protein 4

1

3

Small-scale

0.479

High

590394

CEBPA
CCAAT/enhancer-binding protein alpha

1

4

High-throughput

0.479

High

590395

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

20

High-throughput

0.479

High

590406

MECOM
Histone-lysine N-methyltransferase MECOM

1

2

High-throughput

0.479

High

590407

TLE1
Transducin-like enhancer protein 1

1

20

High-throughput

0.479

High

590408

TLE3
Transducin-like enhancer protein 3

1

20

High-throughput

0.479

High

590409

CSTF1
Cleavage stimulation factor subunit 1

1

13

High-throughput

0.479

High

590410

ZBT16
Zinc finger and BTB domain-containing protein 16

1

1

Small-scale

0.479

High

590411

RING1
E3 ubiquitin-protein ligase RING1

1

18

High-throughput

0.479

High

590412

ZO1
Tight junction protein 1

1

3

Small-scale

0.479

High

590413

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

2

High-throughput

0.479

High

590421

TIF1B
Transcription intermediary factor 1-beta

1

9

High-throughput

0.479

High

590422

IKZF1
DNA-binding protein Ikaros

1

1

Small-scale

0.479

High

590424

HDAC1
Histone deacetylase 1

1

15

Small-scale

0.479

High

590428

GSE1
Genetic suppressor element 1

1

2

High-throughput

0.479

High

590429

ZN638
Zinc finger protein 638

1

4

High-throughput

0.479

High

590438

RBM20
RNA-binding protein 20

1

4

High-throughput

0.479

High

590439

BEND3
BEN domain-containing protein 3

1

3

High-throughput

0.479

High

590443

BCOR
BCL-6 corepressor

1

6

High-throughput

0.479

High

590444

PAXI1
PAX-interacting protein 1

1

7

High-throughput

0.479

High

590449

SUGP2
SURP and G-patch domain-containing protein 2

1

2

High-throughput

0.479

High

590451

CCAR1
Cell division cycle and apoptosis regulator protein 1

1

1

High-throughput

0.479

High

590452

RAVR1
Ribonucleoprotein PTB-binding 1

1

4

High-throughput

0.479

High

590456

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

3

High-throughput

0.479

High

590458

ARI1B
AT-rich interactive domain-containing protein 1B

1

20

High-throughput

0.479

High

590459

KDM2B
Lysine-specific demethylase 2B

1

2

High-throughput

0.479

High

590462

MORC4
MORC family CW-type zinc finger protein 4

1

2

High-throughput

0.479

High

590467

DPF1
Zinc finger protein neuro-d4

1

20

High-throughput

0.479

High

590468

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.479

High

590475

FUBP1
Far upstream element-binding protein 1

1

6

High-throughput

0.479

High

590477

FUBP3
Far upstream element-binding protein 3

1

6

High-throughput

0.479

High

590479

ZFR
Zinc finger RNA-binding protein

1

3

High-throughput

0.479

High

590484

PCGF1
Polycomb group RING finger protein 1

1

16

High-throughput

0.479

High

590497

HM20A
High mobility group protein 20A

1

19

High-throughput

0.479

High

590498

BRD7
Bromodomain-containing protein 7

1

18

High-throughput

0.479

High

590501

RBM12
RNA-binding protein 12

1

5

High-throughput

0.479

High

590505

CPSF2
Cleavage and polyadenylation specificity factor subunit 2

1

1

High-throughput

0.479

High

590506

RCOR3
REST corepressor 3

1

20

High-throughput

0.479

High

590508

SATB2
DNA-binding protein SATB2

1

4

High-throughput

0.479

High

590512

NCOR2
Nuclear receptor corepressor 2

1

13

High-throughput

0.479

High

109363

G5E9A7
DM1 locus, WD repeat containing

1

11

High-throughput

0.470

High

590384

GRN
Progranulin

1

1

High-throughput

0.470

High

590399

KR105
Keratin-associated protein 10-5

1

5

High-throughput

0.470

High

369999

TIMP1
Metalloproteinase inhibitor 1

1

0

Small-scale

0.458

High

507498

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

Small-scale

0.458

High

555329

SKI
Ski oncogene

1

0

Small-scale

0.458

High

584699

NDKA
Nucleoside diphosphate kinase A

1

0

Small-scale

0.458

High

590382

PSA4
Proteasome subunit alpha type-4

1

0

High-throughput

0.458

High

590440

ZN318
Zinc finger protein 318

1

0

High-throughput

0.458

High

590500

MBIP1
MAP3K12-binding inhibitory protein 1

1

0

High-throughput

0.458

High

590504

SENP1
Sentrin-specific protease 1

1

0

Small-scale

0.458

High

259387

BRD4
Bromodomain-containing protein 4

1

11

High-throughput

0.445

High

138552

CLD5
Claudin-5

1

1

Small-scale

0.437

High

590435

OCLN
Occludin

1

1

Small-scale

0.437

High

590495

FBRS
Probable fibrosin-1

1

3

High-throughput

0.437

High

220221

FRS3
Fibroblast growth factor receptor substrate 3

3

0

High-throughput

0.352

High

590455

CCD24
Coiled-coil domain-containing protein 24

3

0

High-throughput

0.352

High

590492

CHRD
Chordin

2

0

High-throughput

0.316

High

590493

ARMC7
Armadillo repeat-containing protein 7

2

0

High-throughput

0.316

High

590463

FBF1
Fas-binding factor 1

1

0

High-throughput

0.299

High

590478

RADIL
Ras-associating and dilute domain-containing protein

1

0

High-throughput

0.299

High

590402

VA0D1
V-type proton ATPase subunit d 1

1

0

High-throughput

0.292

High

590457

PNMA1
Paraneoplastic antigen Ma1

1

0

High-throughput

0.292

High

590466

PSMF1
Proteasome inhibitor PI31 subunit

1

0

High-throughput

0.292

High

245860

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.268

Low

442223

GELS
Gelsolin

1

0

High-throughput

0.268

Low

590386

METK2
S-adenosylmethionine synthase isoform type-2

1

0

High-throughput

0.268

Low

590400

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.268

Low

590513

Q9Y649
GW128

1

0

High-throughput

0.268

Low

590437

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.251

Low

378605

IL2RA
Interleukin-2 receptor subunit alpha

1

0

Small-scale

0.249

Low

567791

PRG2
Bone marrow proteoglycan

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025