Protein: GATA2
Endothelial transcription factor GATA-2 (GATA-binding protein 2)

Gene: GATA2
Organism: Homo sapiens
Interactions: 194
UniProt ID: P23769

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001221 - transcription coregulator binding
GO:0001223 - transcription coactivator binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

662422

FHL3
Four and a half LIM domains protein 3

2

1

High-throughput

0.811

High

662374

RBTN2
Rhombotin-2

1

11

Small-scale

0.740

High

609903

SPI1
Transcription factor PU.1

3

14

Small-scale

0.690

High

662419

SMAD4
Mothers against decapentaplegic homolog 4

3

8

High-throughput

0.685

High

662458

FOG1
Zinc finger protein ZFPM1

3

11

Small-scale

0.667

High

662375

PIT1
Pituitary-specific positive transcription factor 1

2

11

Small-scale

0.646

High

635294

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

2

2

High-throughput

0.628

High

662373

PSA3
Proteasome subunit alpha type-3

2

2

High-throughput

0.628

High

662382

TRI23
E3 ubiquitin-protein ligase TRIM23

2

1

High-throughput

0.628

High

662489

MDFI
MyoD family inhibitor

2

1

High-throughput

0.628

High

662370

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

13

High-throughput

0.618

High

662513

TRPS1
Zinc finger transcription factor Trps1

1

15

High-throughput

0.618

High

662381

MSX2
Homeobox protein MSX-2

2

12

High-throughput

0.606

High

662478

RBPMS
RNA-binding protein with multiple splicing

2

1

High-throughput

0.606

High

662386

TPC10
Trafficking protein particle complex subunit 10

2

0

High-throughput

0.602

High

662486

TPPC9
Trafficking protein particle complex subunit 9

2

0

High-throughput

0.602

High

662522

TPPC4
Trafficking protein particle complex subunit 4

2

0

High-throughput

0.602

High

662449

NT2NA
Notch homolog 2 N-terminal-like protein A

2

0

High-throughput

0.601

High

662414

EP300
Histone acetyltransferase p300

2

20

Small-scale

0.595

High

662474

CBP
CREB-binding protein

2

20

Small-scale

0.595

High

662400

SKP1
S-phase kinase-associated protein 1

2

1

Small-scale

0.584

High

142836

NFIB
Nuclear factor 1 B-type

1

17

High-throughput

0.578

High

473789

NFIC
Nuclear factor 1 C-type

1

18

High-throughput

0.578

High

662416

NFIA
Nuclear factor 1 A-type

1

19

High-throughput

0.578

High

662524

ZBT32
Zinc finger and BTB domain-containing protein 32

2

2

Small-scale

0.576

High

662378

PML
Protein PML

1

9

Small-scale

0.573

High

662412

GOGA2
Golgin subfamily A member 2

2

1

High-throughput

0.573

High

662418

TRAF1
TNF receptor-associated factor 1

1

1

High-throughput

0.573

High

662409

ZBT16
Zinc finger and BTB domain-containing protein 16

1

1

Small-scale

0.561

High

662429

MED1
Mediator of RNA polymerase II transcription subunit 1

1

13

Small-scale

0.561

High

662464

COP1
E3 ubiquitin-protein ligase COP1

1

9

Small-scale

0.561

High

662480

FBXW7
F-box/WD repeat-containing protein 7

1

5

Small-scale

0.561

High

70116

CRTP1
Cysteine-rich tail protein 1

2

2

High-throughput

0.553

High

662436

KR133
Keratin-associated protein 13-3

2

1

High-throughput

0.553

High

662494

KRA31
Keratin-associated protein 3-1

2

1

High-throughput

0.553

High

662379

AKT1
RAC-alpha serine/threonine-protein kinase

1

2

Small-scale

0.550

High

662408

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

2

High-throughput

0.536

High

662394

KR109
Keratin-associated protein 10-9

1

6

High-throughput

0.523

High

662432

OBF1
POU domain class 2-associating factor 1

1

0

High-throughput

0.518

High

662396

SMD3
Small nuclear ribonucleoprotein Sm D3

1

2

High-throughput

0.515

High

301343

WFS1
Wolframin

1

1

High-throughput

0.515

High

662376

CLAT
Choline O-acetyltransferase

1

1

High-throughput

0.515

High

662377

GRN
Progranulin

1

1

High-throughput

0.515

High

662525

RNF11
RING finger protein 11

1

1

High-throughput

0.515

High

605167

TAL1
T-cell acute lymphocytic leukemia protein 1

1

9

Small-scale

0.508

High

429318

JUN
Transcription factor Jun

1

4

Small-scale

0.501

High

443184

CDK1
Cyclin-dependent kinase 1

1

3

Small-scale

0.501

High

662420

HDAC1
Histone deacetylase 1

1

15

Small-scale

0.501

High

662475

KAT2A
Histone acetyltransferase KAT2A

1

20

Small-scale

0.501

High

532366

CH60
60 kDa heat shock protein, mitochondrial

1

3

High-throughput

0.500

High

552506

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

2

High-throughput

0.500

High

662383

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.500

High

662388

EMD
Emerin

1

2

High-throughput

0.500

High

662392

SYMC
Methionine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.500

High

662431

DDB1
DNA damage-binding protein 1

1

1

High-throughput

0.500

High

285592

BAF
Barrier-to-autointegration factor

1

0

High-throughput

0.479

High

484382

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.479

High

662398

RS24
Small ribosomal subunit protein eS24

1

0

High-throughput

0.479

High

138970

BCL9
B-cell CLL/lymphoma 9 protein

1

15

High-throughput

0.479

High

154628

ARI1A
AT-rich interactive domain-containing protein 1A

1

18

High-throughput

0.479

High

161409

KMT2D
Histone-lysine N-methyltransferase 2D

1

16

High-throughput

0.479

High

174310

ZN609
Zinc finger protein 609

1

6

High-throughput

0.479

High

177435

ZN536
Zinc finger protein 536

1

5

High-throughput

0.479

High

180707

TIF1A
Transcription intermediary factor 1-alpha

1

13

High-throughput

0.479

High

188173

HDAC3
Histone deacetylase 3

1

15

Small-scale

0.479

High

194510

KDM6A
Lysine-specific demethylase 6A

1

7

High-throughput

0.479

High

245588

ZEB2
Zinc finger E-box-binding homeobox 2

1

3

High-throughput

0.479

High

246434

KDM1A
Lysine-specific histone demethylase 1A

1

12

High-throughput

0.479

High

261366

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

10

High-throughput

0.479

High

278238

NCOR1
Nuclear receptor corepressor 1

1

18

High-throughput

0.479

High

297460

PIAS1
E3 SUMO-protein ligase PIAS1

1

2

High-throughput

0.479

High

341523

EYA4
Protein phosphatase EYA4

1

10

High-throughput

0.479

High

662397

H4
Histone H4

1

1

High-throughput

0.479

High

344866

WIZ
Protein Wiz

1

3

High-throughput

0.479

High

355142

ACL6A
Actin-like protein 6A

1

1

High-throughput

0.479

High

405800

MYCN
N-myc proto-oncogene protein

1

2

High-throughput

0.479

High

505516

ATX1L
Ataxin-1-like

1

1

High-throughput

0.479

High

549053

CDK4
Cyclin-dependent kinase 4

1

5

Small-scale

0.479

High

586222

ZEP1
Zinc finger protein 40

1

4

High-throughput

0.479

High

629060

CCNA2
Cyclin-A2

1

1

Small-scale

0.479

High

662371

COT2
COUP transcription factor 2

1

8

Small-scale

0.479

High

662372

CDK2
Cyclin-dependent kinase 2

1

3

Small-scale

0.479

High

662380

BMI1
Polycomb complex protein BMI-1

1

16

High-throughput

0.479

High

662384

ZEB1
Zinc finger E-box-binding homeobox 1

1

5

High-throughput

0.479

High

662385

CUX1
Homeobox protein cut-like 1

1

11

High-throughput

0.479

High

662387

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

11

High-throughput

0.479

High

662389

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

20

High-throughput

0.479

High

662390

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

20

High-throughput

0.479

High

662391

ATX1
Ataxin-1

1

1

High-throughput

0.479

High

662395

DCAF7
DDB1- and CUL4-associated factor 7

1

9

High-throughput

0.479

High

662401

SSBP2
Single-stranded DNA-binding protein 2

1

1

High-throughput

0.479

High

662404

SATB1
DNA-binding protein SATB1

1

4

High-throughput

0.479

High

662405

TLE1
Transducin-like enhancer protein 1

1

20

High-throughput

0.479

High

662406

TLE3
Transducin-like enhancer protein 3

1

20

High-throughput

0.479

High

662407

TLE4
Transducin-like enhancer protein 4

1

20

High-throughput

0.479

High

662410

RING1
E3 ubiquitin-protein ligase RING1

1

18

High-throughput

0.479

High

662411

TLE5
TLE family member 5

1

10

High-throughput

0.479

High

662415

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

3

High-throughput

0.479

High

662417

FOXC1
Forkhead box protein C1

1

15

High-throughput

0.479

High

662421

CUL1
Cullin-1

1

3

Small-scale

0.479

High

662424

NCOA6
Nuclear receptor coactivator 6

1

18

High-throughput

0.479

High

662426

ARI5B
AT-rich interactive domain-containing protein 5B

1

18

High-throughput

0.479

High

662427

RBBP5
Retinoblastoma-binding protein 5

1

6

High-throughput

0.479

High

662428

SSXT
Protein SSXT

1

14

High-throughput

0.479

High

662430

ZFHX3
Zinc finger homeobox protein 3

1

6

High-throughput

0.479

High

662437

ARI4B
AT-rich interactive domain-containing protein 4B

1

17

High-throughput

0.479

High

662438

BCL7A
B-cell CLL/lymphoma 7 protein family member A

1

4

High-throughput

0.479

High

662441

ARID2
AT-rich interactive domain-containing protein 2

1

16

High-throughput

0.479

High

662443

NIPBL
Nipped-B-like protein

1

5

High-throughput

0.479

High

662444

MDEAS
Mitotic deacetylase-associated SANT domain protein

1

15

High-throughput

0.479

High

662446

BCOR
BCL-6 corepressor

1

6

High-throughput

0.479

High

662447

PAXI1
PAX-interacting protein 1

1

7

High-throughput

0.479

High

662448

ASXL2
Putative Polycomb group protein ASXL2

1

9

High-throughput

0.479

High

662450

PCGF5
Polycomb group RING finger protein 5

1

16

High-throughput

0.479

High

662451

LDB1
LIM domain-binding protein 1

1

3

High-throughput

0.479

High

662452

PB1
Protein polybromo-1

1

15

High-throughput

0.479

High

662453

ZFHX4
Zinc finger homeobox protein 4

1

5

High-throughput

0.479

High

662457

ARI3B
AT-rich interactive domain-containing protein 3B

1

18

High-throughput

0.479

High

662459

YAF2
YY1-associated factor 2

1

3

High-throughput

0.479

High

662460

RYBP
RING1 and YY1-binding protein

1

3

High-throughput

0.479

High

662461

KMT2C
Histone-lysine N-methyltransferase 2C

1

20

High-throughput

0.479

High

662462

ARI1B
AT-rich interactive domain-containing protein 1B

1

20

High-throughput

0.479

High

662463

KDM2B
Lysine-specific demethylase 2B

1

2

High-throughput

0.479

High

662465

SMRC2
SWI/SNF complex subunit SMARCC2

1

20

High-throughput

0.479

High

662466

CHD6
Chromodomain-helicase-DNA-binding protein 6

1

13

High-throughput

0.479

High

662467

MORC4
MORC family CW-type zinc finger protein 4

1

2

High-throughput

0.479

High

662468

BCL7C
B-cell CLL/lymphoma 7 protein family member C

1

4

High-throughput

0.479

High

662469

FOG2
Zinc finger protein ZFPM2

1

11

High-throughput

0.479

High

662471

ZN516
Zinc finger protein 516

1

3

High-throughput

0.479

High

662472

DPF1
Zinc finger protein neuro-d4

1

20

High-throughput

0.479

High

662473

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.479

High

662476

SMRC1
SWI/SNF complex subunit SMARCC1

1

14

High-throughput

0.479

High

662477

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

10

High-throughput

0.479

High

662479

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

12

High-throughput

0.479

High

662482

ZBTB9
Zinc finger and BTB domain-containing protein 9

1

8

High-throughput

0.479

High

662483

ZN503
Zinc finger protein 503

1

3

High-throughput

0.479

High

662484

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

7

High-throughput

0.479

High

662485

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

3

High-throughput

0.479

High

662487

CIC
Protein capicua homolog

1

18

High-throughput

0.479

High

662488

RING2
E3 ubiquitin-protein ligase RING2

1

18

High-throughput

0.479

High

662490

ARI3A
AT-rich interactive domain-containing protein 3A

1

18

High-throughput

0.479

High

662491

PCGF1
Polycomb group RING finger protein 1

1

16

High-throughput

0.479

High

662493

SSBP3
Single-stranded DNA-binding protein 3

1

7

High-throughput

0.479

High

662495

TBL1R
F-box-like/WD repeat-containing protein TBL1XR1

1

10

High-throughput

0.479

High

662496

SP130
Histone deacetylase complex subunit SAP130

1

6

High-throughput

0.479

High

662498

FOXP1
Forkhead box protein P1

1

15

High-throughput

0.479

High

662499

ZN644
Zinc finger protein 644

1

3

High-throughput

0.479

High

662500

ZN703
Zinc finger protein 703

1

4

High-throughput

0.479

High

662501

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

3

High-throughput

0.479

High

662505

HM20A
High mobility group protein 20A

1

19

High-throughput

0.479

High

662506

BRD7
Bromodomain-containing protein 7

1

18

High-throughput

0.479

High

662507

TF7L2
Transcription factor 7-like 2

1

19

High-throughput

0.479

High

662508

SALL1
Sal-like protein 1

1

5

High-throughput

0.479

High

662510

HM20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

1

19

High-throughput

0.479

High

662511

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

18

High-throughput

0.479

High

662512

RCOR3
REST corepressor 3

1

20

High-throughput

0.479

High

662514

SIX4
Homeobox protein SIX4

1

7

High-throughput

0.479

High

662515

RCOR1
REST corepressor 1

1

20

High-throughput

0.479

High

662516

IKZF3
Zinc finger protein Aiolos

1

1

High-throughput

0.479

High

662517

ZN608
Zinc finger protein 608

1

4

High-throughput

0.479

High

662518

PRR12
Proline-rich protein 12

1

15

High-throughput

0.479

High

662519

SATB2
DNA-binding protein SATB2

1

4

High-throughput

0.479

High

662520

HDAC5
Histone deacetylase 5

1

20

Small-scale

0.479

High

662523

ZN281
Zinc finger protein 281

1

3

High-throughput

0.479

High

662526

NCOR2
Nuclear receptor corepressor 2

1

13

High-throughput

0.479

High

662527

NCOA3
Nuclear receptor coactivator 3

1

5

High-throughput

0.479

High

650053

FGFR3
Fibroblast growth factor receptor 3

1

2

High-throughput

0.470

High

662402

PR20C
Proline-rich protein 20C

1

1

High-throughput

0.470

High

662435

KRA63
Keratin-associated protein 6-3

1

1

High-throughput

0.470

High

662399

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

Small-scale

0.458

High

662440

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

0

High-throughput

0.458

High

662470

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

662481

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

0

High-throughput

0.458

High

662492

PAGR1
PAXIP1-associated glutamate-rich protein 1

1

0

High-throughput

0.458

High

662497

TDIF1
Deoxynucleotidyltransferase terminal-interacting protein 1

1

0

High-throughput

0.458

High

662504

SHCAF
SIN3-HDAC complex-associated factor

1

0

High-throughput

0.458

High

662521

EIF3L
Eukaryotic translation initiation factor 3 subunit L

1

0

High-throughput

0.458

High

457949

TRY1
Serine protease 1

1

1

High-throughput

0.457

High

662413

LG3BP
Galectin-3-binding protein

1

1

High-throughput

0.457

High

662423

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

1

High-throughput

0.457

High

662509

GRHL1
Grainyhead-like protein 1 homolog

1

1

High-throughput

0.445

High

662393

KR103
Keratin-associated protein 10-3

1

6

High-throughput

0.439

High

662403

PR20A
Proline-rich protein 20A

1

1

High-throughput

0.439

High

662425

GSE1
Genetic suppressor element 1

1

2

High-throughput

0.437

High

662433

QSER1
Glutamine and serine-rich protein 1

1

11

High-throughput

0.437

High

662439

PRC2B
Protein PRRC2B

1

13

High-throughput

0.437

High

662502

FBRS
Probable fibrosin-1

1

3

High-throughput

0.437

High

662503

FBSL
Fibrosin-1-like protein

1

3

High-throughput

0.437

High

662434

KR212
Keratin-associated protein 21-2

2

0

High-throughput

0.316

High

662454

KR111
Keratin-associated protein 11-1

2

0

High-throughput

0.316

High

662455

KRA81
Keratin-associated protein 8-1

2

0

High-throughput

0.316

High

662456

KRA71
Keratin-associated protein 7-1

2

0

High-throughput

0.316

High

662442

K1C40
Keratin, type I cytoskeletal 40

1

0

High-throughput

0.299

High

662445

ATL4
ADAMTS-like protein 4

1

0

High-throughput

0.299

High


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Last updated: 11Aug2025