HitPredict

Interactor 1: MET (P08581)
Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)
Gene: MET

Interactor 2: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	11254878, 35384245, 16909210
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0019903 - protein phosphatase binding GO:0031016 - pancreas development GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1390 Hs			1 781
+	Mm
		93667 MET_MOUSE (1-1381): 0: 1246: 89.57		E9Q6A9_MOUSE (467-685): 2.78e-09: 62.7: 18.39
+	Hs
		716907 EPHA5_HUMAN (579-1346): 3.64e-177: 556: 19.08		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		665553 EPHB2_HUMAN (597-1389): 7.92e-156: 500: 18.91		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		717105 EPHA7_HUMAN (587-1389): 6.03e-156: 498: 18.53		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		542243 EPHA5_HUMAN (579-1346): 3.64e-177: 556: 19.08		PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42
+	Hs
		542244 EPHA4_HUMAN (555-1389): 3.08e-175: 549: 17.20		PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42
+	Hs
		542198 EPHB2_HUMAN (597-1389): 7.92e-156: 500: 18.91		PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42
+	Hs
		542333 EPHA7_HUMAN (587-1389): 6.03e-156: 498: 18.53		PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42
+	Hs
		717022 TYRO3_HUMAN (1053-1341): 6.19e-65: 240: 41.67		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		713763 RYK_HUMAN (1078-1334): 2.54e-59: 218: 39.47		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		435557 IGF1R_HUMAN (1084-1337): 2.07e-56: 217: 42.16		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Rn
		544931 INSR_RAT (1084-1335): 3.22e-52: 204: 40.98		CTNB1_RAT (1-781): 0: 625: 99.74
+	Hs
		337371 ABL1_HUMAN (1084-1341): 1.06e-51: 201: 41.38		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		561383 FER_HUMAN (1078-1340): 5.99e-52: 199: 37.36		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		542203 UFO_HUMAN (1078-1333): 5.27e-66: 243: 45.90		PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42
+	Hs
		542212 RYK_HUMAN (1078-1334): 2.54e-59: 218: 39.47		PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42
+	Hs
		435524 IGF1R_HUMAN (1084-1337): 2.07e-56: 217: 42.16		PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42
+	Mm
		546270 INSR_MOUSE (1084-1335): 2.21e-52: 204: 40.98		PLAK_MOUSE (8-752): 6.82e-156: 473: 66.62
+	Hs
		853217 EPHB4_HUMAN (736-1342): 2.91e-128: 424: 21.72		IMA1_HUMAN (237-675): 3.54e-66: 231: 18.54