HitPredict

Interactor 1: GELS (P06396)
Gelsolin (AGEL) (Actin-depolymerizing factor) (ADF) (Brevin)
Gene: GSN

Interactor 2: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.670

Property	Details
Experiments	12941811, 15604093, 19574450
Identification Methods	pull down, two hybrid, t7 phage display
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0010628 - positive regulation of gene expression
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 782 Hs			1 920
+	Hs
		395324 GELS_HUMAN (1-782): 0: 1207: 100.00		ESR1_HUMAN (378-904): 7.63e-136: 420: 22.20
+	Hs
		442427 GELS_HUMAN (1-782): 0: 1207: 100.00		ESR2_HUMAN (435-912): 2.49e-116: 367: 21.51
+	Hs
		1367724 SCIN_HUMAN (51-768): 0: 1007: 59.72		ESR2_HUMAN (435-912): 2.49e-116: 367: 21.51
+	Hs
		519997 FLII_HUMAN (373-765): 2.37e-57: 214: 22.88		ANDR_HUMAN (1-920): 0: 966: 100.00
+	Hs
		336329 SVIL_HUMAN (551-779): 2.12e-24: 112: 21.86		ANDR_HUMAN (1-920): 0: 966: 100.00
+	Hs
		396016 FLII_HUMAN (373-765): 2.37e-57: 214: 22.88		ESR1_HUMAN (378-904): 7.63e-136: 420: 22.20
+	Hs
		403755 VILI_HUMAN (68-467): 1.53e-69: 246: 28.22		GCR_HUMAN (444-920): 1.2e-117: 378: 40.85
+	Hs
		1093283 FLII_HUMAN (373-765): 2.37e-57: 214: 22.88		ESR2_HUMAN (435-912): 2.49e-116: 367: 21.51
+	Hs
		336312 SVIL_HUMAN (551-779): 2.12e-24: 112: 21.86		ESR1_HUMAN (378-904): 7.63e-136: 420: 22.20
+	Hs
		336315 SVIL_HUMAN (551-779): 2.12e-24: 112: 21.86		GCR_HUMAN (444-920): 1.2e-117: 378: 40.85