HitPredict

Interactor 1: HCK (P08631)
Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)
Gene: HCK

Interactor 2: HSP76 (P17066)
Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B') (Heat shock protein family A member 6)
Gene: HSPA6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 526 Hs			1 643
+	Hs
		442767 HCK_HUMAN (1-526): 0: 635: 100.00		HSP7C_HUMAN (4-615): 0: 940: 79.25
+	Hs
		411586 LCK_HUMAN (23-526): 0: 581: 64.89		HSP76_HUMAN (1-643): 0: 970: 100.00
+	Hs
		503340 SRC_HUMAN (1-524): 0: 582: 54.51		HSP7C_HUMAN (4-615): 0: 940: 79.25
+	Hs
		411570 LCK_HUMAN (23-526): 0: 581: 64.89		HSP7C_HUMAN (4-615): 0: 940: 79.25
+	Hs
		433227 YES_HUMAN (1-524): 0: 570: 56.77		HSP7C_HUMAN (4-615): 0: 940: 79.25
+	Hs
		411965 FYN_HUMAN (22-524): 0: 564: 57.79		HSP7C_HUMAN (4-615): 0: 940: 79.25
+	Hs
		503608 ABL2_HUMAN (17-523): 5.55e-166: 503: 38.06		HSP7C_HUMAN (4-615): 0: 940: 79.25
+	Hs
		337324 ABL1_HUMAN (47-523): 1.77e-166: 502: 39.38		HSP7C_HUMAN (4-615): 0: 940: 79.25
+	Hs
		789047 ABL2_HUMAN (17-523): 5.55e-166: 503: 38.06		HSP72_HUMAN (3-643): 0: 925: 77.45
+	Hs
		564074 PTK6_HUMAN (72-520): 7.27e-156: 453: 40.00		HSP76_HUMAN (1-643): 0: 970: 100.00
+	Hs
		504053 PTK6_HUMAN (72-520): 7.27e-156: 453: 40.00		HSP7C_HUMAN (4-615): 0: 940: 79.25