HitPredict

Interactor 1: RASK (P08644)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: Kras

Interactor 2: Q6P751 (Q6P751)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2)
Gene: Cdk2

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	1.00	0.806

Property	Details
Experiments	22045811, 11384971
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 189 Rn			1 298
+	Hs
		349133 RASH_HUMAN (1-188): 3.11e-87: 256: 86.77		CDK2_HUMAN (1-298): 1.46e-166: 465: 98.99
+	Hs
		625461 RB11B_HUMAN (4-176): 5.49e-73: 221: 34.29		CDK2_HUMAN (1-298): 1.46e-166: 465: 98.99
+	Hs
		348617 RASN_HUMAN (1-189): 3.17e-86: 253: 86.24		CDK5_HUMAN (1-292): 1.73e-138: 394: 59.73
+	Hs
		349801 RASK_HUMAN (1-189): 6.74e-78: 232: 98.94		CDK1_HUMAN (1-289): 2.57e-143: 406: 66.55
+	Hs
		625297 RRAS2_HUMAN (3-188): 1.47e-54: 173: 54.12		CDK2_HUMAN (1-298): 1.46e-166: 465: 98.99
+	Hs
		350079 RASK_HUMAN (1-189): 6.74e-78: 232: 98.94		CDK17_HUMAN (1-296): 1.24e-123: 365: 52.19
+	Hs
		348618 RASN_HUMAN (1-189): 3.17e-86: 253: 86.24		CDK16_HUMAN (1-286): 1.2e-107: 323: 55.75
+	Dm
		618430 RALA_DROME (4-182): 3.08e-60: 187: 52.22		CDK2_DROME (1-298): 1.04e-133: 383: 62.08
+	Hs
		960367 RAB35_HUMAN (4-187): 2.06e-83: 246: 31.28		CDK16_HUMAN (1-286): 1.2e-107: 323: 55.75
+	Hs
		350078 RASK_HUMAN (1-189): 6.74e-78: 232: 98.94		CDK16_HUMAN (1-286): 1.2e-107: 323: 55.75
+	Hs
		914011 RB11A_HUMAN (4-184): 2.07e-74: 224: 33.88		CDK16_HUMAN (1-286): 1.2e-107: 323: 55.75
+	Hs
		895041 RAB2A_HUMAN (4-182): 1.27e-73: 222: 32.60		CDK16_HUMAN (1-286): 1.2e-107: 323: 55.75