HitPredict

Interactor 1: RAP1 (P08645)
Ras-related protein Rap1 (EC 3.6.5.2) (Rap1 GTPase) (Ras-like protein 3)
Gene: RAP1

Interactor 2: Q24279 (Q24279)
Cno
Gene: cno

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.24	1.00	0.492

Property	Details
Experiments	unassigned4
Identification Methods	experimental interaction detection
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DIL~Ras, PDZ~Ras, RA~Ras
Common GO terms	GO:0007391 - dorsal closure
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 184 Dm			1 1893
+	Dm
		442967 RAP1_DROME (1-184): 7.38e-88: 257: 100.00		Q95TT5_DROME (1-524): 0: 668: 94.68
+	Hs
		876348 RAP1A_HUMAN (1-184): 1.49e-87: 256: 85.95		AFAD_HUMAN (445-1624): 1.79e-126: 442: 28.78
+	Dm
		442960 RAP1_DROME (1-184): 7.38e-88: 257: 100.00		Q8IPP3_DROME (463-1595): 8.99e-115: 406: 44.62
+	Hs
		914382 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		KI13B_HUMAN (130-1603): 2.05e-67: 255: 10.45
+	Hs
		914383 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		MYO5C_HUMAN (94-782): 3.41e-66: 251: 14.03
+	Hs
		919631 RAP1A_HUMAN (1-184): 1.49e-87: 256: 85.95		KIF14_HUMAN (130-638): 2.24e-56: 219: 12.55
+	Hs
		914346 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		KI13A_HUMAN (273-637): 6.15e-63: 240: 16.93
+	Hs
		914486 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		MYO5A_HUMAN (141-777): 1.97e-59: 229: 14.43
+	Hs
		918872 RAB1A_HUMAN (4-170): 5.46e-76: 228: 34.52		KIF14_HUMAN (130-638): 2.24e-56: 219: 12.55
+	Hs
		914285 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		KI16B_HUMAN (62-736): 2.16e-57: 221: 16.23
+	Hs
		1066669 RAB1B_HUMAN (4-170): 1.78e-75: 226: 32.74		KIF14_HUMAN (130-638): 2.24e-56: 219: 12.55
+	Hs
		914453 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		MYO5B_HUMAN (102-801): 7.32e-57: 220: 13.46
+	Rn
		914521 RB11A_RAT (4-179): 6.45e-75: 225: 28.81		MYO5B_RAT (130-801): 2.46e-56: 219: 12.26
+	Hs
		1079976 RB11B_HUMAN (4-176): 1.4e-73: 222: 29.89		MYO5B_HUMAN (102-801): 7.32e-57: 220: 13.46
+	Dm
		51909 O18335_DROME (4-176): 6.54e-75: 225: 31.03		A1Z6Z9_DROME (491-768): 6.43e-50: 198: 14.02
+	Hs
		914375 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		GOPC_HUMAN (580-1018): 1.04e-53: 198: 14.80
+	Mm
		918987 RAB1A_MOUSE (4-170): 5.46e-76: 228: 34.52		NEB2_MOUSE (826-961): 1.61e-38: 158: 34.53
+	Mm
		895596 RAB8B_MOUSE (4-180): 8.19e-73: 219: 33.15		NEB2_MOUSE (826-961): 1.61e-38: 158: 34.53
+	Hs
		919668 RAP1A_HUMAN (1-184): 1.49e-87: 256: 85.95		RADIL_HUMAN (757-941): 1.47e-21: 104: 22.16
+	Hs
		914066 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		SCRIB_HUMAN (741-1068): 7.12e-24: 112: 15.62