Protein: MTMR3
Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) (Zinc finger FYVE domain-containing protein 10)

Gene: MTMR3
Organism: Homo sapiens
Interactions: 66
UniProt ID: Q13615

Gene Ontology (top 5):
GO:0004438 - phosphatidylinositol-3-phosphate phosphatase activity
GO:0004722 - protein serine/threonine phosphatase activity
GO:0004725 - protein tyrosine phosphatase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1040957

MTMR4
Myotubularin-related protein 4

5

18

Small-scale

0.919

High

1040928

MTMR3
Myotubularin-related protein 3

2

17

High-throughput

0.754

High

160556

AURKA
Aurora kinase A

5

6

High-throughput

0.714

High

683328

1433B
14-3-3 protein beta/alpha

3

20

High-throughput

0.662

High

904536

1433G
14-3-3 protein gamma

3

20

High-throughput

0.662

High

981990

1433F
14-3-3 protein eta

3

20

High-throughput

0.662

High

861742

PLK1
Serine/threonine-protein kinase PLK1

3

7

High-throughput

0.656

High

1040955

PNO1
RNA-binding protein PNO1

3

0

High-throughput

0.638

High

456322

LOX5
Polyunsaturated fatty acid 5-lipoxygenase

2

1

High-throughput

0.628

High

1040936

DJC10
DnaJ homolog subfamily C member 10

2

4

High-throughput

0.628

High

1040929

CUL3
Cullin-3

2

7

High-throughput

0.611

High

1040931

LONF1
LON peptidase N-terminal domain and RING finger protein 1

2

10

High-throughput

0.606

High

1040954

EXOS5
Exosome complex component RRP46

2

2

High-throughput

0.606

High

262448

TULP3
Tubby-related protein 3

2

1

High-throughput

0.574

High

1040944

HDA11
Histone deacetylase 11

2

4

High-throughput

0.574

High

1040948

MED18
Mediator of RNA polymerase II transcription subunit 18

2

1

High-throughput

0.574

High

601507

FGFR2
Fibroblast growth factor receptor 2

1

20

High-throughput

0.541

High

253004

HSF2B
Heat shock factor 2-binding protein

1

1

High-throughput

0.536

High

312918

SLU7
Pre-mRNA-splicing factor SLU7

1

1

High-throughput

0.536

High

787479

MTOR
Serine/threonine-protein kinase mTOR

1

8

Small-scale

0.536

High

801692

RAGP1
Ran GTPase-activating protein 1

1

2

High-throughput

0.536

High

909535

1433E
14-3-3 protein epsilon

1

8

High-throughput

0.536

High

927016

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

1031517

ATM
Serine-protein kinase ATM

1

7

High-throughput

0.536

High

1040938

RPTOR
Regulatory-associated protein of mTOR

1

7

Small-scale

0.536

High

1040950

LST8
Target of rapamycin complex subunit LST8

1

3

Small-scale

0.536

High

1040953

EGLN3
Prolyl hydroxylase EGLN3

1

3

High-throughput

0.536

High

1040956

ABCF3
ATP-binding cassette sub-family F member 3

1

1

High-throughput

0.536

High

1040958

GTSE1
G2 and S phase-expressed protein 1

1

1

High-throughput

0.536

High

1040959

AIPL1
Aryl-hydrocarbon-interacting protein-like 1

1

3

High-throughput

0.536

High

673476

MPIP2
M-phase inducer phosphatase 2

1

0

High-throughput

0.513

High

606847

IL10
Interleukin-10

1

1

High-throughput

0.489

High

661255

S10A2
Protein S100-A2

1

6

High-throughput

0.489

High

1040940

THOC2
THO complex subunit 2

1

1

High-throughput

0.489

High

1040945

DIESL
DGAT1/2-independent enzyme synthesizing storage lipids

1

1

High-throughput

0.489

High

127263

IPO5
Importin-5

1

2

High-throughput

0.479

High

166924

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

2

High-throughput

0.479

High

294810

RECQ4
ATP-dependent DNA helicase Q4

1

5

High-throughput

0.479

High

319827

HERC2
E3 ubiquitin-protein ligase HERC2

1

4

High-throughput

0.479

High

1040932

CEP55
Centrosomal protein of 55 kDa

1

1

High-throughput

0.479

High

1040933

SYNE3
Nesprin-3

1

10

High-throughput

0.479

High

1040934

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.479

High

1040937

MIRO2
Mitochondrial Rho GTPase 2

1

20

High-throughput

0.479

High

1040942

NU205
Nuclear pore complex protein Nup205

1

2

High-throughput

0.479

High

1040947

EYA3
Eyes absent homolog 3

1

1

High-throughput

0.479

High

1040960

WRP73
WD repeat-containing protein WRAP73

1

2

High-throughput

0.479

High

550384

ZEP1
Zinc finger protein 40

1

0

High-throughput

0.460

High

217801

ORC4
Origin recognition complex subunit 4

1

0

High-throughput

0.458

High

1040949

DERL1
Derlin-1

1

0

High-throughput

0.458

High

1040951

HEAT1
HEAT repeat-containing protein 1

1

0

High-throughput

0.458

High

1040963

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.458

High

1040930

EXOS7
Exosome complex component RRP42

1

1

Small-scale

0.457

High

1040943

EXOS8
Exosome complex component RRP43

1

1

Small-scale

0.457

High

374197

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.445

High

1040962

EXOS1
Exosome complex component CSL4

1

0

Small-scale

0.438

High

1040939

MISSL
MAPK-interacting and spindle-stabilizing protein-like

1

1

High-throughput

0.437

High

1040941

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

1

High-throughput

0.437

High

1040946

ZDH15
Palmitoyltransferase ZDHHC15

1

1

Small-scale

0.437

High

517243

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.417

High

1040935

TLK2
Serine/threonine-protein kinase tousled-like 2

1

6

High-throughput

0.407

High

306403

NDUA3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

1

0

High-throughput

0.279

Low

1040952

STN1
CST complex subunit STN1

1

0

High-throughput

0.279

Low

1040961

TF3C4
General transcription factor 3C polypeptide 4

1

0

High-throughput

0.279

Low

981236

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.249

Low

886280

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024