HitPredict

Interactor 1: K1C19 (P08727)
Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)
Gene: KRT19

Interactor 2: IF4A3 (P38919)
Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed]
Gene: EIF4A3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23084401
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 400 Hs			1 411
+	Hs
		359308 K1C14_HUMAN (78-391): 5.81e-143: 416: 70.38		IF4A3_HUMAN (1-411): 1.22e-142: 414: 100.00
+	Hs
		445011 K1C16_HUMAN (76-397): 5.27e-140: 409: 70.19		IF4A3_HUMAN (1-411): 1.22e-142: 414: 100.00
+	Hs
		133821 K1C14_HUMAN (78-391): 5.81e-143: 416: 70.38		DDX3X_HUMAN (17-410): 2.28e-129: 388: 32.45
+	Hs
		133865 K1C13_HUMAN (74-388): 7.1e-141: 410: 70.57		DDX3X_HUMAN (17-410): 2.28e-129: 388: 32.45
+	Hs
		133848 K1C16_HUMAN (76-397): 5.27e-140: 409: 70.19		DDX3X_HUMAN (17-410): 2.28e-129: 388: 32.45
+	Hs
		133991 K1C17_HUMAN (28-393): 1.38e-139: 406: 67.76		DDX3X_HUMAN (17-410): 2.28e-129: 388: 32.45
+	Hs
		531329 K1C10_HUMAN (75-385): 1.75e-120: 363: 65.29		IF4A3_HUMAN (1-411): 1.22e-142: 414: 100.00
+	Hs
		133864 K1C10_HUMAN (75-385): 1.75e-120: 363: 65.29		DDX3X_HUMAN (17-410): 2.28e-129: 388: 32.45
+	Hs
		318784 K2C75_HUMAN (9-399): 2.51e-89: 281: 26.46		IF4A3_HUMAN (1-411): 1.22e-142: 414: 100.00
+	Hs
		757638 K2C71_HUMAN (5-399): 3.68e-84: 267: 24.43		IF4A3_HUMAN (1-411): 1.22e-142: 414: 100.00
+	Hs
		380447 K2C6B_HUMAN (47-399): 3.73e-79: 255: 24.79		IF4A3_HUMAN (1-411): 1.22e-142: 414: 100.00
+	Hs
		531537 K2C5_HUMAN (47-399): 1.07e-78: 255: 25.35		IF4A3_HUMAN (1-411): 1.22e-142: 414: 100.00
+	Hs
		133831 K2C6B_HUMAN (47-399): 3.73e-79: 255: 24.79		DDX3X_HUMAN (17-410): 2.28e-129: 388: 32.45
+	Hs
		133866 K2C5_HUMAN (47-399): 1.07e-78: 255: 25.35		DDX3X_HUMAN (17-410): 2.28e-129: 388: 32.45
+	Hs
		133822 K2C6A_HUMAN (47-399): 7.08e-78: 252: 25.07		DDX3X_HUMAN (17-410): 2.28e-129: 388: 32.45
+	Hs
		280531 KRT34_HUMAN (73-388): 2.74e-118: 351: 55.06		DDX6_HUMAN (35-407): 1.15e-88: 278: 37.83