HitPredict - High confidence protein-protein interactions

Interactor 1: GNAI3 (P08754)
Guanine nucleotide-binding protein G(i) subunit alpha-3 (G(i) alpha-3)
Gene: GNAI3

Interactor 2: GNAI1 (P63096)
Guanine nucleotide-binding protein G(i) subunit alpha-1 (Adenylate cyclase-inhibiting G alpha protein)
Gene: GNAI1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.895

Property	Details
Experiments	33961781, 26186194, 28514442, 36652389
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	G-alpha~G-alpha
Common GO terms	GO:0001664 - G protein-coupled receptor binding GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005654 - nucleoplasm GO:0005730 - nucleolus and 13 others more... GO:0005737 - cytoplasm GO:0005765 - lysosomal membrane GO:0005813 - centrosome GO:0005834 - heterotrimeric G-protein complex GO:0005886 - plasma membrane GO:0007049 - cell cycle GO:0007188 - adenylate cyclase-modulating G protein-coupled receptor signaling pathway GO:0007193 - adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway GO:0019003 - GDP binding GO:0030496 - midbody GO:0031683 - G-protein beta/gamma-subunit complex binding GO:0051301 - cell division GO:0070062 - extracellular exosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1	354
Hs

1	354

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Last updated: 15 Jul 2024