HitPredict

Interactor 1: K1C16 (P08779)
Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)
Gene: KRT16

Interactor 2: SHC1 (P29353)
SHC-transforming protein 1 (SHC-transforming protein 3) (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1)
Gene: SHC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 473 Hs			1 583
+	Hs
		359306 K1C14_HUMAN (1-448): 6.76e-154: 447: 83.48		SHC1_HUMAN (1-583): 0: 531: 100.00
+	Hs
		531449 K1C13_HUMAN (105-441): 5.96e-141: 413: 69.82		SHC1_HUMAN (1-583): 0: 531: 100.00
+	Hs
		666076 K1C17_HUMAN (62-464): 3.17e-139: 408: 69.31		SHC1_HUMAN (1-583): 0: 531: 100.00
+	Hs
		531323 K1C10_HUMAN (112-422): 7.57e-130: 390: 67.52		SHC1_HUMAN (1-583): 0: 531: 100.00
+	Hs
		1071309 K1H1_HUMAN (67-443): 1.23e-142: 416: 51.72		SHC3_HUMAN (6-582): 3.32e-127: 387: 45.47
+	Hs
		1071190 K1H1_HUMAN (67-443): 1.23e-142: 416: 51.72		Q49AR9_HUMAN (40-425): 1.96e-47: 176: 18.14
+	Hs
		129174 K1C16_HUMAN (1-461): 1.58e-161: 467: 100.00		P85B_HUMAN (358-581): 2.69e-29: 125: 17.47
+	Hs
		1071311 K1H1_HUMAN (67-443): 1.23e-142: 416: 51.72		ANS1A_HUMAN (40-393): 2.28e-42: 165: 18.41
+	Hs
		442835 K1H1_HUMAN (67-443): 1.23e-142: 416: 51.72		HCK_HUMAN (348-575): 2.72e-43: 164: 17.16
+	Hs
		129196 K1C15_HUMAN (116-429): 2.97e-155: 450: 76.19		P85B_HUMAN (358-581): 2.69e-29: 125: 17.47
+	Hs
		129154 K1C14_HUMAN (1-448): 6.76e-154: 447: 83.48		P85B_HUMAN (358-581): 2.69e-29: 125: 17.47
+	Hs
		445027 K1C16_HUMAN (1-461): 1.58e-161: 467: 100.00		GRB2_HUMAN (482-578): 1.65e-15: 77.5: 30.48
+	Hs
		129281 K1C17_HUMAN (62-464): 3.17e-139: 408: 69.31		P85B_HUMAN (358-581): 2.69e-29: 125: 17.47
+	Hs
		580010 K1C15_HUMAN (116-429): 2.97e-155: 450: 76.19		GRB2_HUMAN (482-578): 1.65e-15: 77.5: 30.48
+	Hs
		359329 K1C14_HUMAN (1-448): 6.76e-154: 447: 83.48		GRB2_HUMAN (482-578): 1.65e-15: 77.5: 30.48
+	Hs
		129187 K1C10_HUMAN (112-422): 7.57e-130: 390: 67.52		P85B_HUMAN (358-581): 2.69e-29: 125: 17.47
+	Hs
		444346 K1C19_HUMAN (106-434): 2.34e-146: 425: 69.61		GRB2_HUMAN (482-578): 1.65e-15: 77.5: 30.48
+	Hs
		280492 KT33A_HUMAN (63-443): 2.97e-140: 410: 51.44		GRB2_HUMAN (482-578): 1.65e-15: 77.5: 30.48
+	Hs
		924493 K1C17_HUMAN (62-464): 3.17e-139: 408: 69.31		GRB2_HUMAN (482-578): 1.65e-15: 77.5: 30.48
+	Hs
		531343 K1C10_HUMAN (112-422): 7.57e-130: 390: 67.52		GRB2_HUMAN (482-578): 1.65e-15: 77.5: 30.48