HitPredict

Interactor 1: K1C16 (P08779)
Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)
Gene: KRT16

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned1853
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 473 Hs			1 2527
+	Hs
		359367 K1C14_HUMAN (1-448): 6.76e-154: 447: 83.48		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		980269 K1C17_HUMAN (62-464): 3.17e-139: 408: 69.31		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		531379 K1C10_HUMAN (112-422): 7.57e-130: 390: 67.52		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		72923 B4DN72_HUMAN (8-428): 3.28e-97: 302: 25.83		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130283 K2C73_HUMAN (5-431): 1.11e-94: 298: 24.94		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		380486 K2C6B_HUMAN (27-447): 1.75e-75: 248: 24.82		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		531584 K2C5_HUMAN (82-431): 2.58e-74: 246: 26.14		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		3119 A0A0S2Z428_HUMAN (27-447): 3.16e-74: 245: 25.06		LRRK2_HUMAN (1-2527): 0: 3008: 99.72