Interactor 1: IL6RA (P08887)
Interleukin-6 receptor subunit alpha (IL-6 receptor subunit alpha) (IL-6R subunit alpha) (IL-6R-alpha) (IL-6RA) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD antigen CD126) [Cleaved into: Soluble interleukin-6 receptor subunit alpha (sIL6R)]
Gene: IL6R

Interactor 2: CNTF (P26441)
Ciliary neurotrophic factor (CNTF)
Gene: CNTF

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 0.60 0.629

The method score is based on:

Property Details
Experiments 12643274, 1281789
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0008284 - positive regulation of cell population proliferation
GO:0042531 - positive regulation of tyrosine phosphorylation of STAT protein
GO:0070120 - ciliary neurotrophic factor-mediated signaling pathway
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 468
Hs

1 200
+ Hs
+ Hs
+ Mm
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+ Mm
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Last updated: 15 Jul 2024