HitPredict

Interactor 1: ROS1 (P08922)
Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)
Gene: ROS1

Interactor 2: SERPH (P50454)
Serpin H1 (47 kDa heat shock protein) (Arsenic-transactivated protein 3) (AsTP3) (Cell proliferation-inducing gene 14 protein) (Collagen-binding protein) (Colligin) (Rheumatoid arthritis-related antigen RA-A47)
Gene: SERPINH1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 2347 Hs			1 418
+	Rn
		403561 INSR_RAT (1424-2308): 1.37e-164: 549: 23.18		SPA3K_RAT (5-409): 3.49e-160: 459: 23.97
+	Hs
		411337 INSR_HUMAN (1424-2308): 7.33e-167: 555: 23.13		SERPH_HUMAN (1-418): 7.1e-152: 438: 100.00
+	Hs
		435588 IGF1R_HUMAN (1442-2307): 3.63e-161: 538: 23.25		SERPH_HUMAN (1-418): 7.1e-152: 438: 100.00
+	Hs
		674366 UFO_HUMAN (1633-2297): 6.04e-130: 434: 25.83		SERPH_HUMAN (1-418): 7.1e-152: 438: 100.00
+	Hs
		839705 ALK_HUMAN (1858-2311): 4.31e-84: 309: 38.96		SERPH_HUMAN (1-418): 7.1e-152: 438: 100.00
+	Hs
		609214 FGFR3_HUMAN (1886-2215): 4.22e-59: 222: 38.73		SERPH_HUMAN (1-418): 7.1e-152: 438: 100.00