HitPredict

Interactor 1: LAM0 (P08928)
Lamin Dm0
Gene: Lam

Interactor 2: IMA (P52295)
Importin subunit alpha (Karyopherin subunit alpha) (Pendulin)
Gene: Pen

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.600

Property	Details
Experiments	22384376, 14605208
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 622 Dm			1 522
+	Hs
		134820 LMNA_HUMAN (25-579): 1.03e-50: 188: 36.15		IMA3_HUMAN (6-522): 1.08e-144: 427: 45.84
+	Hs
		131360 LMNA_HUMAN (25-579): 1.03e-50: 188: 36.15		IMA4_HUMAN (2-522): 1.47e-141: 419: 44.53
+	Hs
		359783 LMNA_HUMAN (25-579): 1.03e-50: 188: 36.15		IMA1_HUMAN (8-522): 3.38e-139: 414: 49.04
+	Hs
		595158 LMNB1_HUMAN (24-622): 1.44e-51: 188: 35.83		IMA1_HUMAN (8-522): 3.38e-139: 414: 49.04
+	Dr
		71547 B3DKC5_DANRE (28-588): 2.38e-47: 178: 34.21		Q7ZVY9_DANRE (9-522): 1.37e-142: 422: 45.72
+	Hs
		238622 LMNA_HUMAN (25-579): 1.03e-50: 188: 36.15		IMA7_HUMAN (2-521): 2.91e-134: 401: 46.53
+	Hs
		238630 LMNB1_HUMAN (24-622): 1.44e-51: 188: 35.83		IMA7_HUMAN (2-521): 2.91e-134: 401: 46.53
+	Hs
		168609 LMNA_HUMAN (25-579): 1.03e-50: 188: 36.15		IMA6_HUMAN (2-521): 2.16e-130: 391: 45.71
+	Hs
		168617 LMNB1_HUMAN (24-622): 1.44e-51: 188: 35.83		IMA6_HUMAN (2-521): 2.16e-130: 391: 45.71
+	Ce
		1091055 LMN1_CAEEL (50-574): 9.68e-57: 202: 31.52		IMA3_CAEEL (6-522): 3.92e-124: 374: 44.98
+	Hs
		359784 LMNA_HUMAN (25-579): 1.03e-50: 188: 36.15		IMA5_HUMAN (2-521): 3.58e-126: 381: 42.75
+	Hs
		595159 LMNB1_HUMAN (24-622): 1.44e-51: 188: 35.83		IMA5_HUMAN (2-521): 3.58e-126: 381: 42.75