HitPredict

Interactor 1: SNRPA (P09012)
U1 small nuclear ribonucleoprotein A (U1 snRNP A) (U1-A) (U1A)
Gene: SNRPA

Interactor 2: RNPS1 (Q15287)
RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2)
Gene: RNPS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.867

Property	Details
Experiments	26496610, 17353931, 35271311
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 282 Hs			1 305
+	Hs
		446637 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		SART3_HUMAN (2-302): 1.67e-38: 146: 16.32
+	Hs
		441287 RU2B_HUMAN (5-282): 1.37e-59: 190: 46.40		SART3_HUMAN (2-302): 1.67e-38: 146: 16.32
+	Hs
		441291 RU2B_HUMAN (5-282): 1.37e-59: 190: 46.40		RNPS1_HUMAN (1-234): 2e-34: 128: 100.00
+	Hs
		446841 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		PPIE_HUMAN (159-297): 4.41e-33: 125: 17.73
+	Hs
		198830 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		RFOX2_HUMAN (44-274): 2.32e-31: 122: 13.25
+	Hs
		441393 RU2B_HUMAN (5-282): 1.37e-59: 190: 46.40		PPIE_HUMAN (159-297): 4.41e-33: 125: 17.73
+	Hs
		198843 PTBP1_HUMAN (1-281): 2.58e-55: 189: 20.42		RFOX2_HUMAN (44-274): 2.32e-31: 122: 13.25
+	Hs
		446860 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		RBM8A_HUMAN (95-239): 7.02e-31: 115: 21.38
+	Hs
		446547 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		NCBP2_HUMAN (128-271): 1.08e-30: 114: 18.06
+	Hs
		441401 RU2B_HUMAN (5-282): 1.37e-59: 190: 46.40		RBM8A_HUMAN (95-239): 7.02e-31: 115: 21.38
+	Hs
		643457 PTBP1_HUMAN (1-281): 2.58e-55: 189: 20.42		NCBP2_HUMAN (128-271): 1.08e-30: 114: 18.06
+	Hs
		321252 PTBP3_HUMAN (2-281): 3.29e-49: 172: 19.44		PPIE_HUMAN (159-297): 4.41e-33: 125: 17.73
+	Hs
		198821 PTBP3_HUMAN (2-281): 3.29e-49: 172: 19.44		RFOX2_HUMAN (44-274): 2.32e-31: 122: 13.25
+	Hs
		1070496 RBY1F_HUMAN (1-280): 7.88e-46: 162: 17.48		RNPS1_HUMAN (1-234): 2e-34: 128: 100.00
+	Sc
		696674 RU1A_YEAST (1-281): 3.81e-48: 163: 20.42		NCBP2_YEAST (127-236): 1.25e-33: 124: 25.46
+	Hs
		321022 PTBP3_HUMAN (2-281): 3.29e-49: 172: 19.44		NCBP2_HUMAN (128-271): 1.08e-30: 114: 18.06
+	Hs
		446592 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		TIAR_HUMAN (155-250): 1.9e-18: 86.5: 27.08
+	Hs
		446516 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		TIA1_HUMAN (156-251): 3.47e-18: 85.7: 27.08
+	Hs
		320990 PTBP3_HUMAN (2-281): 3.29e-49: 172: 19.44		TIA1_HUMAN (156-251): 3.47e-18: 85.7: 27.08
+	At
		1115085 Q9ASW4_ARATH (11-281): 7.72e-45: 156: 22.91		CP29A_ARATH (108-252): 8.48e-20: 90: 20.00